Ignite Creation Date:
2024-05-06 @ 8:24 PM
Last Modification Date:
2024-10-26 @ 3:27 PM
Study NCT ID:
NCT06371586
Status:
RECRUITING
Last Update Posted:
2024-04-17
First Post:
2024-04-14
Brief Title:
Neo-Sequence 2NCT Plus Anti-angiogenesis Therapy and Immunotherapy for LADGC
Sponsor:
Cancer Institute and Hospital Chinese Academy of Medical Sciences
Organization:
Cancer Institute and Hospital Chinese Academy of Medical Sciences
Study Overview
Official Title:
Neo-Sequence 2Phase 2 Study of Neoadjuvant Chemotherapy Plus Anti-angiogenesis Therapy and Immunotherapy for Locally Advanced Diffuse Gastric Cancer
Status:
RECRUITING
Status Verified Date:
2024-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The regimen of Albumin paclitaxelSOXBEV neoadjuvant therapy lasted for 6 cycles during which PD-1 monoclonal antibody therapy was interspersed for 4 cycles for locally advanced diffuse gastric cancer
Detailed Description:
The biweekly regimen of Albumin paclitaxelSOXBEV neoadjuvant therapy lasted for 6 cycles during which PD-1 monoclonal antibody therapy was interspersed for 4 cycles Review CT and gastroscopy every 3 cycles to evaluate the therapeutic effect Patients who have been evaluated as effective after 6 cycles of treatment may consider surgery Or continue the dual cycle regimen ofAlbumin paclitaxelBevacizumab for 3 cycles while PD-1 monoclonal antibody for 2 cycles Afterwards the therapeutic effect will be evaluated and surgery radiotherapy or maintenance medication treatment will be determined based on the therapeutic effect Surgical patients begin adjuvant treatment 1-2 months after surgery based on the curative and pathological results of the surgery Those who fail to evaluate during neoadjuvant therapy will undergo surgery or radiation therapy or switch to a second-line systemic treatment plan
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None