Ignite Creation Date:
2024-05-06 @ 8:24 PM
Last Modification Date:
2024-10-26 @ 3:26 PM
Study NCT ID:
NCT06365411
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-04-24
First Post:
2024-03-10
Brief Title:
GEnomic Medicine in Kidney Transplantation Study
Sponsor:
Western Sydney Local Health District
Organization:
Western Sydney Local Health District
Study Overview
Official Title:
GEnomic Medicine in Kidney Transplantation Study
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
GEM-KiT
Brief Summary:
Investigator led prospective observational cohort study to detect genomic features which can predict outcomes following kidney transplantation
1 Determine non-HLA genomic mismatches between donor-recipient pairs which impact kidney allograft survival following transplantation
2 Derive polygenic risk scores on pre-transplant blood andor kidney biopsy samples which predict kidney allograft dysfunction
3 Derive polygenic risk scores on post-transplant blood andor kidney biopsy samples which predict kidney allograft dysfunction
1 Determine non-HLA genomic mismatches between donor-recipient pairs which impact kidney allograft survival following transplantation
2 Derive polygenic risk scores on pre-transplant blood andor kidney biopsy samples which predict kidney allograft dysfunction
3 Derive polygenic risk scores on post-transplant blood andor kidney biopsy samples which predict kidney allograft dysfunction
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None