Ignite Creation Date:
2024-05-06 @ 8:23 PM
Last Modification Date:
2024-10-26 @ 3:26 PM
Study NCT ID:
NCT06363071
Status:
RECRUITING
Last Update Posted:
2024-04-12
First Post:
2024-03-28
Brief Title:
APA and PAS Training for Gait Initiation in Parkinsons Disease
Sponsor:
Chang Gung University
Organization:
Chang Gung University
Study Overview
Official Title:
Gait-initiation Related APA Training in Individuals With Parkinson Disease -Explicit Training and Paired Associative StimulationPAS Priming
Status:
RECRUITING
Status Verified Date:
2024-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Our research focused on understanding the interplay between brain excitability and balance function in patients with Parkinsons disease PD alongside evaluating effective physical therapy methods It highlights the prevalence of non-motor disorders and cognitive impairments among PD patients including balance and postural issues cognitive function decline and gait instability Additionally it notes that PD patients exhibit abnormal electrophysiological responses indicating altered central excitability
Detailed Description:
Research on Brain Excitability and Balance Function Performance in Patients with Parkinsons Disease and Related Physical Therapy Methods
Research indicates that non-motor disorders and cognitive impairments are prevalent in most patients with Parkinsons disease These include balance issues postural instability impaired cognitive functions like working memory and executive functions and gait instability Additionally electrophysiological phenomena in Parkinsons disease patients reveal abnormal central excitatory and inhibitory responses compared to healthy individuals
This experiment seeks to investigate the link between motor performance and brain excitability in patients with Parkinsons disease Previous studies suggest that associative electrical stimulation used to regulate sensorimotor information integration can enhance brain excitability in both healthy individuals and those with Parkinsons disease However the optimal parameters for this stimulation remain uncertain
Furthermore balance exercise training can improve motor performance in Parkinsons disease patients This study aims to determine if various designs of associative electrical stimulation parameters can help these patients achieve optimal brain excitability regulation The combined approach of this stimulation and balance exercise training aims to maintain and improve the patients functional performance thereby enhancing the safety of their daily activities
Research indicates that non-motor disorders and cognitive impairments are prevalent in most patients with Parkinsons disease These include balance issues postural instability impaired cognitive functions like working memory and executive functions and gait instability Additionally electrophysiological phenomena in Parkinsons disease patients reveal abnormal central excitatory and inhibitory responses compared to healthy individuals
This experiment seeks to investigate the link between motor performance and brain excitability in patients with Parkinsons disease Previous studies suggest that associative electrical stimulation used to regulate sensorimotor information integration can enhance brain excitability in both healthy individuals and those with Parkinsons disease However the optimal parameters for this stimulation remain uncertain
Furthermore balance exercise training can improve motor performance in Parkinsons disease patients This study aims to determine if various designs of associative electrical stimulation parameters can help these patients achieve optimal brain excitability regulation The combined approach of this stimulation and balance exercise training aims to maintain and improve the patients functional performance thereby enhancing the safety of their daily activities
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None