Ignite Creation Date:
2024-05-06 @ 8:23 PM
Last Modification Date:
2024-10-26 @ 3:27 PM
Study NCT ID:
NCT06368830
Status:
RECRUITING
Last Update Posted:
2024-07-03
First Post:
2024-04-10
Brief Title:
Oral and Swallowing Function in Older Adults
Sponsor:
University of Wisconsin Madison
Organization:
University of Wisconsin Madison
Study Overview
Official Title:
Characterizing Oral and Swallowing Function in Older Adults Presenting to the Emergency Department
Status:
RECRUITING
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is to learn about oral and swallowing function in older adults presenting to the emergency department The hypothesis is that older adults often have problems with oral and swallowing function and these problems relate to other conditions Study activities are done during the emergency department visit and include providing saliva samples completing a bedside water swallow test completing oral function assessments completing respiratory function tests and answering survey questions
Detailed Description:
Oropharyngeal dysphagia is characterized by changes in swallow event timing biomechanics and pressure generation that occur with advancing age resulting in aspiration of bacteria-laden saliva food and liquid into the lungs Currently oral and swallowing function is not routinely or comprehensively assessed in older adults despite poor oral health and oropharyngeal dysphagia being known risk factors for pneumonia the leading infectious cause of mortality among adults 65 This study seeks to extensively characterize oral and swallowing function in older adults presenting to the emergency department to clarify the relationship of oral hypofunction dysphagia and the upper airway microbiome To achieve this aim study procedures include a bedside dysphagia screen oral health assessment tongue pressure measurement masticatory function assessment respiratory function tests salivary compositional analysis oral microbiome analysis and microphysiological system analysis which applies saliva samples to a bronchiolar lumen model to mimic aspiration and quantify cellular and tissue responses to the saliva microbiome and secreted mediators
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| Protocol Version 62524 | OTHER | UW Madison | None |
| A534100 | OTHER | None | None |