Ignite Creation Date:
2024-05-06 @ 8:23 PM
Last Modification Date:
2024-10-26 @ 3:26 PM
Study NCT ID:
NCT06367127
Status:
ENROLLING_BY_INVITATION
Last Update Posted:
2024-04-16
First Post:
2024-01-15
Brief Title:
Utility of the Clamping Bean Test CBT for Covert Hepatic Encephalopathy Screening
Sponsor:
Shanghai Changzheng Hospital
Organization:
Shanghai Changzheng Hospital
Study Overview
Official Title:
Utility of the Clamping Bean Test CBT for Covert Hepatic Encephalopathy Screening in Cirrhotic Patients
Status:
ENROLLING_BY_INVITATION
Status Verified Date:
2024-01
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Hepatic encephalopathy is a brain dysfunction caused by liver insufficiency andor porto-systemic shunt It manifests as a wide spectrum of neurological or psychiatric abnormalities ranging from subclinical alterations to coma According to the symptoms it is classified as covert HE CHE and overt HE OHE CHE can progress to OHE and is associated with reduced driving ability increased risk of accidents and hospitalization and weakened health-related quality of life resulting in poor prognosis and socio-economic status However due to the absence of readily identifiable clinical symptoms and signs CHE is often neglected in clinical practice
Presently the diagnosis of CHE depends on psychometric and neurophysiological tests including the psychometric hepatic encephalopathy score PHES critical flicker frequency CFF test continuous reaction time CRT test inhibitory control test the SCAN test and electroencephalography Among them PHES is most widely used and recommended by several guidelines However it is difficult to screen CHE among all cirrhotic patients in the clinic using PHES because of the time required and a dependence on trained experts
Moving beans from one container to another with tweezers involves dexterity agility and coordinationThe hypothesis was that the utility of the Clamping Bean Test CBT will enable early screening patients with CHE
Presently the diagnosis of CHE depends on psychometric and neurophysiological tests including the psychometric hepatic encephalopathy score PHES critical flicker frequency CFF test continuous reaction time CRT test inhibitory control test the SCAN test and electroencephalography Among them PHES is most widely used and recommended by several guidelines However it is difficult to screen CHE among all cirrhotic patients in the clinic using PHES because of the time required and a dependence on trained experts
Moving beans from one container to another with tweezers involves dexterity agility and coordinationThe hypothesis was that the utility of the Clamping Bean Test CBT will enable early screening patients with CHE
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None