Ignite Creation Date:
2024-05-06 @ 8:23 PM
Last Modification Date:
2024-10-26 @ 3:27 PM
Study NCT ID:
NCT06368271
Status:
COMPLETED
Last Update Posted:
2024-04-16
First Post:
2024-04-05
Brief Title:
Acute Effects of Dietary Medium-chain Fatty Acids on Lipid Profile
Sponsor:
University of Copenhagen
Organization:
University of Copenhagen
Study Overview
Official Title:
Acute Effects of Dietary Medium-chain Fatty Acids on Llipid Profile
Status:
COMPLETED
Status Verified Date:
2024-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
Lipidomix
Brief Summary:
In the present study the plasma lipid profile was elucidated in healthy lean males by the use of lipidomic analysis in the hours after an acute intake of medium-chain fatty acids MCT and long chain fatty acids LCT respectively In addition oxygen uptake was measured to study energy turnover
Detailed Description:
Four participants ingested MCT or LCT oil on two test days with one-week period between the experimental days The day prior to the experimental days the participants consumed a eucaloric control diet and abstained from alcohol and vigorous physical activity to ensure similar conditions on experimental days
On the test days participants arrived by passive transport in the overnight fasted state 12 h at 8 am and a catheter was inserted into an antecubital vein Following 30 min in supine rest an overnight-fasted basal venous blood sample was obtained Subsequently participants ingested the same test drink as in study 1 containing 35g of MCT or LCT oil diluted in 100g of low-fat low-carbohydrate cocoa milk within five min 100 ml water was provided together with the test drink Venous blood samples were drawn every 30 min for the first two hours and every 60 minutes for the last two hours following intake Participants rested in a bed throughout the test day this This process was repeated on the second test day
On the test days participants arrived by passive transport in the overnight fasted state 12 h at 8 am and a catheter was inserted into an antecubital vein Following 30 min in supine rest an overnight-fasted basal venous blood sample was obtained Subsequently participants ingested the same test drink as in study 1 containing 35g of MCT or LCT oil diluted in 100g of low-fat low-carbohydrate cocoa milk within five min 100 ml water was provided together with the test drink Venous blood samples were drawn every 30 min for the first two hours and every 60 minutes for the last two hours following intake Participants rested in a bed throughout the test day this This process was repeated on the second test day
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None