Ignite Creation Date:
2024-05-06 @ 8:22 PM
Last Modification Date:
2024-10-26 @ 3:26 PM
Study NCT ID:
NCT06356415
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-04-10
First Post:
2024-04-04
Brief Title:
Infraclavicular Brachial Plexus Block With Bupivacaine Alone or With Both Dexmedetomidine and Dexamethasone
Sponsor:
Suez Canal University
Organization:
Suez Canal University
Study Overview
Official Title:
Infraclavicular Brachial Plexus Block Using Bupivacaine Alone or in Combination With Dexmedetomidine and Dexamethasone for Hand and Forearm Surgeries A Randomized Controlled Trial
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Upper-extremity regional anesthetic techniques using brachial plexus blockade have been shown to reduce adverse effects related to opioid administration improve patient satisfaction and provide significantly improved analgesia immediately following these surgeries Many medications have been investigated to extend and enhance long-acting local anesthetics LA analgesic effects Currently dexamethasone and dexmedetomidine have been studied looking for an optimal long-lasting single-shot nerve block In general adjuvants have been used in peripheral nerve blocks to accelerate onset decrease plasmatic absorption and secondary toxic effects and prolong the block effects
Detailed Description:
Brachial plexus blockade-based upper-extremity regional anesthetic approaches have been demonstrated to lessen opioid administration side effects increase patient satisfaction and offer noticeably better analgesia right after these surgeries A lot of drugs have been tested to prolong and improve the analgesic effect of long-acting local anesthetics LA Currently dexamethasone and dexmedetomidine have been studied looking for an optimal long-lasting single-shot nerve block Adjuvants have generally been employed in peripheral nerve blocks to lengthen the block effects limit secondary toxic effects and plasmatic absorption and speed the onset of the block Objectives To compare the effects of adding dexmedetomidine and dexamethasone to bupivacaine on the start of sensory blockade in an infraclavicular brachial plexus block Patients and Methods A prospective randomized controlled trial will be conducted on patients who are undergoing hand or forearm surgeries Patients who will be eligible for the study will be divided into 2 groups The first group will receive dexmedetomidine and dexamethasone as adjuvants to bupivacaine while the second group will receive bupivacaine alone Expected Results The success rate onset time duration of the block and possible adverse events
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None