Ignite Creation Date:
2024-05-06 @ 8:22 PM
Last Modification Date:
2024-10-26 @ 3:26 PM
Study NCT ID:
NCT06354504
Status:
COMPLETED
Last Update Posted:
2024-04-09
First Post:
2024-03-07
Brief Title:
Bactericidal Permeability Protein Inhibitor and Interleukin-1beta Levels After Non-surgical Periodontal Treatment
Sponsor:
Akdeniz University
Organization:
Akdeniz University
Study Overview
Official Title:
Gingival Crevicular Fluid GCF BactericidalPermeability-increasing Protein BPI and Interleukin IL-1beta in Periodontitis Patients Non-surgical Periodontal Treatment Effects
Status:
COMPLETED
Status Verified Date:
2024-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The aim of this study was to examine the relationship between healing response after non-surgical periodontal treatment and baseline gingival crevicular fluid GCF levels of bactericidalpermeability-increasing protein BPI and interleukin-1beta IL-1ß
Detailed Description:
Bactericidalpermeability-increasing proteins BPI specific and powerful effect against Gram negative bacteria and their LPSs is completely observable in biological fluids such as plasma serum and whole blood
Objective It is the evaluation of periodontal disease effect of BPI and interleukin-1 beta IL-1 β levels in gingival fluid before and after non-surgical periodontal treatment NSPTin patients with periodontal disease
Method Thirty systemically healthy and non-smoking individuals with periodontitis were included in the study Before NSPT the clinical parameters of plaque index PI gingival index GI probing depth PD clinical attachment level CAS bleeding on probing BOP were measured The gingival fluid samples were taken using the paper strip method The same procedures were repeated at 6 weeks and 6 months after non-surgical periodontal treatment ELISA method was used for the analysis of the samples
Objective It is the evaluation of periodontal disease effect of BPI and interleukin-1 beta IL-1 β levels in gingival fluid before and after non-surgical periodontal treatment NSPTin patients with periodontal disease
Method Thirty systemically healthy and non-smoking individuals with periodontitis were included in the study Before NSPT the clinical parameters of plaque index PI gingival index GI probing depth PD clinical attachment level CAS bleeding on probing BOP were measured The gingival fluid samples were taken using the paper strip method The same procedures were repeated at 6 weeks and 6 months after non-surgical periodontal treatment ELISA method was used for the analysis of the samples
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None