Ignite Creation Date:
2024-05-06 @ 8:21 PM
Last Modification Date:
2024-10-26 @ 3:26 PM
Study NCT ID:
NCT06353035
Status:
ACTIVE_NOT_RECRUITING
Last Update Posted:
2024-04-08
First Post:
2024-03-27
Brief Title:
Biodiversity Interventions for Well-Being
Sponsor:
Natural Resources Institute Finland
Organization:
Natural Resources Institute Finland
Study Overview
Official Title:
Biodiversity Interventions for Well-being Neighborhood Rewilding
Status:
ACTIVE_NOT_RECRUITING
Status Verified Date:
2024-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
BIWE
Brief Summary:
Biodiversity is essential for nature and human well-being Land use has reduced biodiversity in cities which weakens the functionality of the urban ecosystems and the well-being of citizens This may also increase the risk of immune-mediated disorders among urban dwellers
In Biodiversity interventions for well-being BIWE microbial biodiversity interventions are performed to increase biodiversity in urban built areas Results from the intervention trials are combined with publicly available land cover and ecological data These are analyzed from the viewpoint of shifts in ecosystems and human well-being and immune regulation ecological quality and urban planning
The investigators set up an intervention study in which urban private yards are rewilded with diverse vegetation and decaying deadwood and plant residuals The investigators aim to evaluate the effect of rewilding and yard management practices on commensal microbiome cortisol levels and well-being and salivary cytokine levels and gene pathways
In Biodiversity interventions for well-being BIWE microbial biodiversity interventions are performed to increase biodiversity in urban built areas Results from the intervention trials are combined with publicly available land cover and ecological data These are analyzed from the viewpoint of shifts in ecosystems and human well-being and immune regulation ecological quality and urban planning
The investigators set up an intervention study in which urban private yards are rewilded with diverse vegetation and decaying deadwood and plant residuals The investigators aim to evaluate the effect of rewilding and yard management practices on commensal microbiome cortisol levels and well-being and salivary cytokine levels and gene pathways
Detailed Description:
Our specific aims are
To assess if rewilding diversifies health-associated skin microbiota and is associated with salivary cytokine levels gene pathways cortisol levels and commensal microbiota
Assess whether there are patterns in the microbiome associated with the salivary cytokine levels and hair cortisol levels
Assess whether rewilding affects health and psychological measures such as Perceived Stress Scale PSS Warwick-Edinburgh Mental Wellbeing Scale SWEMWS Depression Scale DEPS and Nature Relatedness Scale NR6
The investigators will recruit approximately 42 21 study subjects per treatment subjects living in a detached house or terraced house in urban areas and aged between 18-72
The medical exclusion criteria include immunosuppressive medications immune deficiencies a disease affecting immune response eg colitis ulcerosa rheumatoid arthritis Crohns disease diabetes cancer diagnosis within the last year or on-going cancer treatment Other exclusion criteria include incompetency and living outside city area
To assess if rewilding diversifies health-associated skin microbiota and is associated with salivary cytokine levels gene pathways cortisol levels and commensal microbiota
Assess whether there are patterns in the microbiome associated with the salivary cytokine levels and hair cortisol levels
Assess whether rewilding affects health and psychological measures such as Perceived Stress Scale PSS Warwick-Edinburgh Mental Wellbeing Scale SWEMWS Depression Scale DEPS and Nature Relatedness Scale NR6
The investigators will recruit approximately 42 21 study subjects per treatment subjects living in a detached house or terraced house in urban areas and aged between 18-72
The medical exclusion criteria include immunosuppressive medications immune deficiencies a disease affecting immune response eg colitis ulcerosa rheumatoid arthritis Crohns disease diabetes cancer diagnosis within the last year or on-going cancer treatment Other exclusion criteria include incompetency and living outside city area
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 346136 | OTHER_GRANT | None | None |
| 346138 | OTHER_GRANT | Strategic Research Council Finland | None |