Ignite Creation Date:
2024-05-06 @ 8:21 PM
Last Modification Date:
2024-10-26 @ 3:26 PM
Study NCT ID:
NCT06355830
Status:
RECRUITING
Last Update Posted:
2024-04-09
First Post:
2023-03-07
Brief Title:
Intermediate Age-related Macular Degeneration - Multimodal Analysis and Longitudinal Study
Sponsor:
Universidade Nova de Lisboa
Organization:
Universidade Nova de Lisboa
Study Overview
Official Title:
Intermediate Age-related Macular Degeneration - Multimodal Analysis and Longitudinal Study
Status:
RECRUITING
Status Verified Date:
2024-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
Imaging4iAMD
Brief Summary:
Study observational prospective clinical study Study population Subjects over 55 years old with drusen secondary to intermediate AMD
Recruitment at the Medical Retinal Consultation from the Ophthalmology Department of CHULC
Primary outcome Identifying imaging predictors of iAMD progression
Recruitment at the Medical Retinal Consultation from the Ophthalmology Department of CHULC
Primary outcome Identifying imaging predictors of iAMD progression
Detailed Description:
Individuals will be included consecutively and undergo retinal imaging including Color Fundus photography CFP Spectral Domain Optical Coherence Tomography SD-OCT OCT-Angiography OCT-A using Spectralis OCT with OCT Angiography Module Heidelberg Eng GmbH Germany in order to characterize
A FUNDUS AUTOFLUORESCENCE
1 Analyse the correlation between drusen morphology and autofluorescent findings
2 Analyse the correlation between outer retinal layers morphology and autofluorescent findings
3 Assess anatomic biomarkers of disease progression
B VASCULAR FINDINGS
1 Test if choriocapillaris perfusion is disturbed in Intermediate AMD patients
2 Test if retinal capillary plexus perfusion is disturbed in Intermediate AMD patients
21 Analyze superficial retinal capillary plexus SCP 22 Analyze deep retinal capillary plexus DCP
3 Assess if choroidal and retinal vascular changes are related to disease progression
A FUNDUS AUTOFLUORESCENCE
1 Analyse the correlation between drusen morphology and autofluorescent findings
2 Analyse the correlation between outer retinal layers morphology and autofluorescent findings
3 Assess anatomic biomarkers of disease progression
B VASCULAR FINDINGS
1 Test if choriocapillaris perfusion is disturbed in Intermediate AMD patients
2 Test if retinal capillary plexus perfusion is disturbed in Intermediate AMD patients
21 Analyze superficial retinal capillary plexus SCP 22 Analyze deep retinal capillary plexus DCP
3 Assess if choroidal and retinal vascular changes are related to disease progression
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None