Ignite Creation Date:
2024-05-06 @ 8:21 PM
Last Modification Date:
2024-10-26 @ 3:25 PM
Study NCT ID:
NCT06346834
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-04-15
First Post:
2024-01-29
Brief Title:
Sequential Vaccination of Poliomyelitis Vaccine Vero Cells Inactivated Sabin Strains From Different Manufacturers
Sponsor:
Sinovac Biotech Co Ltd
Organization:
Sinovac Biotech Co Ltd
Study Overview
Official Title:
A Study to Evaluate the Immunogenicity and Safety of Sequential Vaccination Among Infants With Poliomyelitis Vaccine Vero Cells Inactivated Sabin Strains Hereinafter as sIPV From Different Manufacturers
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To evaluate the immunogenicity and safety of sequential vaccination with Sinovac sIPV among infants who have received two doses of Biological Products Co Ltd sIPV
Detailed Description:
In this study two hundred infants 12 months of age vaccinated with two doses of sIPV produced by Beijing Institute of Biological Products Co Ltd will be enrolled with a balanced male-to-female ratio After enrollment with informed consent from the guardians of the participants they will be divided into two groups ie the study group and the control group according to the 11 ratio They will be vaccinated with one dose of the sIPV produced by Sinovac or the sIPV produced by Beijing Institute respectively The 30-minute observation will be conducted after the vaccination Immediate reactions will be observed and solicited adverse events within 0-7 days while unsolicited adverse events within 0-30 days will be collected to evaluate vaccine safety About 25-30 ml of venous blood will be collected from all participants before and 30 days after vaccination and anti-poliovirus type 1 type 2 and type 3 neutralizing antibody tests will be performed to evaluate immunogenicity
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None