Ignite Creation Date:
2024-05-06 @ 8:21 PM
Last Modification Date:
2024-10-26 @ 3:25 PM
Study NCT ID:
NCT06349369
Status:
RECRUITING
Last Update Posted:
2024-04-25
First Post:
2024-04-01
Brief Title:
Effect of tDCS on Inflammatory Biomarkers in Chronic Schizophrenia
Sponsor:
All India Institute of Medical Sciences Bhubaneswar
Organization:
All India Institute of Medical Sciences Bhubaneswar
Study Overview
Official Title:
Effect of Transcranial Direct Current Stimulation tDCS on Inflammatory Biomarkers in Chronic Schizophrenia A Randomised Double-Blind Controlled Trial
Status:
RECRUITING
Status Verified Date:
2024-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
tDCS
Brief Summary:
The study is a randomized double-blind parallel-arm sham-controlled trial that aims to compare the effects of transcranial direct current stimulation tDCS versus sham stimulation on inflammatory markers IL-6 and TNF-alpha and clinical outcomes PANSS AHRS CGI-SCH GAF in patients with chronic schizophrenia over 10 days of treatment The primary objective is to assess changes in IL-6 levels while secondary objectives include evaluating changes in TNF-alpha symptom scales and adverse events The study will be conducted at the psychiatry department of AIIMS Bhubaneswar with 60 patients aged 18-60 years with moderate-to-severe schizophrenia symptoms randomized to receive either active tDCS cathode over left temporo-parietal junction anode over left dorsolateral prefrontal cortex or sham stimulation The researchers hope to elucidate the potential immunomodulatory effects of tDCS and its impact on symptoms in chronic schizophrenia which may lead to more targeted multifaceted interventions to improve patient outcomes
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None