Ignite Creation Date:
2024-05-06 @ 8:21 PM
Last Modification Date:
2024-10-26 @ 3:25 PM
Study NCT ID:
NCT06349447
Status:
RECRUITING
Last Update Posted:
2024-04-05
First Post:
2024-04-01
Brief Title:
Pilot Study of LED for PIE and PIH
Sponsor:
Yanjun Dan
Organization:
Huashan Hospital
Study Overview
Official Title:
The Therapeutic and Preventive Effects of Light-emitting Diodes LEDs Irradiation for Post-inflammatory Erythema and Hyperpigmentation a Self-controlled
Status:
RECRUITING
Status Verified Date:
2024-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The aim of this study is to explore the effect of medical LEDs 830 nm and 590 nm in the prevention and treatment of PIE and PIH
Detailed Description:
Evidence regarding the efficacy of LEDs for post-inflammatory erythema PIE and post-inflammatory hyperpigmentation PIH is limited
The aim of this study was to evaluate the efficacy of 830 nm and 590 nm LED phototherapies on PIE and PIH
Design of the study
308 nm LED light 15 MED induced an in vivo PIEPIH model on the thigh of ten healthy subjects 830 nm 60 Jcm2 and 590 nm LED 20 Jcm2 were irradiated respectively For therapeutic irradiation PIEPIH model was induced on D1 and LEDs were irradiated on D0 1 3 6 and 8 For preventive irradiation LEDs were irradiated on D0 1 3 6 and 8 and PIEPIH model was induced on D9 Erythema index EI melanin index MI transdermal water loss TEWL and C-Cube photography were measured during 10-day follow-up visits
The aim of this study was to evaluate the efficacy of 830 nm and 590 nm LED phototherapies on PIE and PIH
Design of the study
308 nm LED light 15 MED induced an in vivo PIEPIH model on the thigh of ten healthy subjects 830 nm 60 Jcm2 and 590 nm LED 20 Jcm2 were irradiated respectively For therapeutic irradiation PIEPIH model was induced on D1 and LEDs were irradiated on D0 1 3 6 and 8 For preventive irradiation LEDs were irradiated on D0 1 3 6 and 8 and PIEPIH model was induced on D9 Erythema index EI melanin index MI transdermal water loss TEWL and C-Cube photography were measured during 10-day follow-up visits
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None