Ignite Creation Date:
2024-05-06 @ 8:21 PM
Last Modification Date:
2024-10-26 @ 3:25 PM
Study NCT ID:
NCT06345859
Status:
RECRUITING
Last Update Posted:
2024-05-13
First Post:
2024-03-28
Brief Title:
Regulation of Affect and Physiology in Depression
Sponsor:
University of Southern California
Organization:
University of Southern California
Study Overview
Official Title:
Ambulatory Phenotyping With Real-Time Indices of Discordant Affect Regulation Exploring Opportunities for Targeted Intervention in Depression
Status:
RECRUITING
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
RAPID
Brief Summary:
Although treatments for depression are effective for many people not everyone responds to treatment This lack of treatment response could be due in part to the presence of multiple underlying causes of peoples depression This study aims to identify subtypes of depression based on two factors how successful people perceive themselves to be at regulating their affect in everyday life and how much activity in the parasympathetic nervous system increases during moments when people try to regulate The study involves ambulatory assessment of affect regulation strategies and physiological activity in everyday life in a sample of young adults with remitted major depressive disorder and healthy volunteers We will study regulation responses in the lab to further determine how subtypes differ in neural physiological and behavioral responses Finally participants will be randomly assigned to a remote self-administered biofeedback intervention vs control intervention designed to increase parasympathetic activity and physiological regulation success While engaging in biofeedback at home for 10 days participants will simultaneously repeat the ambulatory assessments This design will allow us to determine the proximal impact of biofeedback on indices of regulation success in everyday life and whether biofeedback has differential impact on regulation success for different subtypes
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| R01MH133842 | NIH | None | httpsreporternihgovquickSearchR01MH133842 |