Ignite Creation Date:
2024-05-06 @ 8:20 PM
Last Modification Date:
2024-10-26 @ 3:25 PM
Study NCT ID:
NCT06345963
Status:
RECRUITING
Last Update Posted:
2024-04-05
First Post:
2024-03-28
Brief Title:
Enhancing Brain Connectivity in Schizophrenia Through Neuromodulation Study 1
Sponsor:
The University of Texas Health Science Center Houston
Organization:
The University of Texas Health Science Center Houston
Study Overview
Official Title:
Enhancing Brain Connectivity in Schizophrenia Through Neuromodulation Study 1
Status:
RECRUITING
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Patients with schizophrenia spectrum disorder SSD will be exposed to active repetitive transcranial magnetic stimulation rTMS from H coil for improving white matter integrity
Detailed Description:
Schizophrenia is a severe mental illness that affects about 1 of the population but a major source of disability Information processing between brain regions occurs due to transfer of electrical impulses among them This process is determined by the existing neuronalfiber connections which may be altered and or modified in the presence of neuronal stimulation or cognitive intervention The frontal lobe information flow is critical for higher cognitive functions thought processes and proper emotional and behavioral responses Improving the myelination in the frontal lobe may increase cognitive functions and reduce risks to develop symptoms of schizophrenia The investigators propose that increasing electrical signaling in the frontal white matter in patients with schizophrenia may also enhance myelination and improve the white matter integrity
The patients with schizophrenia will receive active repetitive transcranial magnetic stimulation rTMS treatment The rTMS with H coil is FDA-cleared for short-term smoking cessation in the general population Its efficacy in myelination modulation has not been evaluated
The patients with schizophrenia will receive active repetitive transcranial magnetic stimulation rTMS treatment The rTMS with H coil is FDA-cleared for short-term smoking cessation in the general population Its efficacy in myelination modulation has not been evaluated
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
True
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
False
Is an FDA AA801 Violation?:
None