Ignite Creation Date:
2024-05-05 @ 7:02 PM
Last Modification Date:
2024-10-26 @ 9:41 AM
Study NCT ID:
NCT00594659
Status:
COMPLETED
Last Update Posted:
2013-12-04
First Post:
2008-01-07
Brief Title:
Development and Efficacy Test of Computerized Treatment for Marijuana Dependence
Sponsor:
Dartmouth-Hitchcock Medical Center
Organization:
Dartmouth-Hitchcock Medical Center
Study Overview
Official Title:
Development and Efficacy Test of Computerized Treatment for Marijuana Dependence
Status:
COMPLETED
Status Verified Date:
2013-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
More US residents are dependent on marijuana than on any other illicit drug and the number enrolled in treatment for marijuana continues to increase such that it is now comparable to that for cocaine and heroin This application seeks to advance the overarching goal to develop and disseminate cost-effective treatments for marijuana dependence that can address this growing problem
The researchers previous research suggests that an intervention comprising motivational enhancement cognitive-behavioral and contingency-management components METCBTCM produces greater rates of successful and durable outcomes than has been demonstrated previously However three issues relevant to its efficacy and eventual dissemination must be confronted First the outcomes achieved can only be characterized as modest many individuals do not respond to the treatment and relapse rates remain problematic Second access is limited by the availability of trained providers Third the cost of delivering the treatment is higher than more traditional outpatient interventions
To address these issues Specific Aim 1 is to develop and test a computer-assisted version of METCBTCM Computerized treatments have the potential to increase overall effectiveness of treatment services by increasing availability of and access to potent treatments and by applying innovative technology to enhance outcomes During Year 1 the intervention will be developed and pilot tested An interactive program that showed promise in a previous trial for opioid dependence will be modified and enhanced to deliver individualized METCBTCM using effective computer learning technologies These technologies and access to the METCBTCM program made available via the Internet between treatment sessions and after treatment ends have the potential to promote better learning and more use of coping skills which in turn can improve outcomes During Years 2-4 a randomized trial will provide an initial efficacy test of cMETCBTCM by comparing it with a brief treatment MET and with therapist-delivered METCBTCM Specific Aim 2 is to learn more about how behavioral treatments like METCBTCM work by focusing on two putative mechanisms of action examined in prior trials self-efficacycoping skills and impulsivitydelay discounting The experimental design will provide a unique opportunity to explore such mechanisms in a novel context- where the therapist is vs is not a prominent part of the treatment
The proposed project will address the objectives of NIDAs Behavioral and Integrative Treatment Development Program by providing research on technology-assisted treatment that attempts to make treatment delivery less complex easier to access and less costly - while retaining or improving its effectiveness Findings will inform future studies designed to refine the technology and how it is applied conduct more definitive effectiveness testing test generality to other populations including adolescents and to further advance translation to community settings
The researchers previous research suggests that an intervention comprising motivational enhancement cognitive-behavioral and contingency-management components METCBTCM produces greater rates of successful and durable outcomes than has been demonstrated previously However three issues relevant to its efficacy and eventual dissemination must be confronted First the outcomes achieved can only be characterized as modest many individuals do not respond to the treatment and relapse rates remain problematic Second access is limited by the availability of trained providers Third the cost of delivering the treatment is higher than more traditional outpatient interventions
To address these issues Specific Aim 1 is to develop and test a computer-assisted version of METCBTCM Computerized treatments have the potential to increase overall effectiveness of treatment services by increasing availability of and access to potent treatments and by applying innovative technology to enhance outcomes During Year 1 the intervention will be developed and pilot tested An interactive program that showed promise in a previous trial for opioid dependence will be modified and enhanced to deliver individualized METCBTCM using effective computer learning technologies These technologies and access to the METCBTCM program made available via the Internet between treatment sessions and after treatment ends have the potential to promote better learning and more use of coping skills which in turn can improve outcomes During Years 2-4 a randomized trial will provide an initial efficacy test of cMETCBTCM by comparing it with a brief treatment MET and with therapist-delivered METCBTCM Specific Aim 2 is to learn more about how behavioral treatments like METCBTCM work by focusing on two putative mechanisms of action examined in prior trials self-efficacycoping skills and impulsivitydelay discounting The experimental design will provide a unique opportunity to explore such mechanisms in a novel context- where the therapist is vs is not a prominent part of the treatment
The proposed project will address the objectives of NIDAs Behavioral and Integrative Treatment Development Program by providing research on technology-assisted treatment that attempts to make treatment delivery less complex easier to access and less costly - while retaining or improving its effectiveness Findings will inform future studies designed to refine the technology and how it is applied conduct more definitive effectiveness testing test generality to other populations including adolescents and to further advance translation to community settings
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 1R01DA023526-03 | NIH | None | httpsreporternihgovquickSearch1R01DA023526-03 |
| 1R01DA023526-01 | NIH | None | None |
| 1R01DA023526-02 | NIH | None | None |