Ignite Creation Date:
2024-05-06 @ 8:19 PM
Last Modification Date:
2024-10-26 @ 3:25 PM
Study NCT ID:
NCT06336473
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-06-24
First Post:
2024-03-21
Brief Title:
Evaluation of the Effects of Cross Linking on the Biomechanical Characteristics of Skin Samples From Patients With Classic or Hypermobile Ehlers-Danlos Syndrome
Sponsor:
GCS Ramsay Santé pour lEnseignement et la Recherche
Organization:
GCS Ramsay Santé pour lEnseignement et la Recherche
Study Overview
Official Title:
Evaluation of the Effects of Cross Linking on the Biomechanical Characteristics of Skin Samples From Patients With Classic or Hypermobile Ehlers-Danlos Syndrome
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
SEDSKIN
Brief Summary:
The main aim of this study is to evaluate the effect of cross linking on the elasticity of skin samples from patients with non-vascular Ehlers-Danlos Syndrome hEDS or cEDS
Detailed Description:
This is a single-center study based on skin biopsies The skin biopsies will be taken at the non-vascular Ehlers-Danlos syndromes reference center at the Raymond Poincaré Hospital Garches by Dr Karelle Benistan This center regularly performs this type of biopsy as part of its routine care and has set up a fibroblast bank for Genethon Authorization for biological collection at Genethon SED BACG n DC-2021-4628
Samples will be transported to the Centre de Recherche Saint-Antoine UMR-S 938 where they will be processed cut and placed on histological slides
Atomic force microscopy analyses will be carried out at the Laboratoire de Réactivité de Surface CNRSSorbonne University
Samples will be transported to the Centre de Recherche Saint-Antoine UMR-S 938 where they will be processed cut and placed on histological slides
Atomic force microscopy analyses will be carried out at the Laboratoire de Réactivité de Surface CNRSSorbonne University
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None