Ignite Creation Date:
2024-05-06 @ 8:19 PM
Last Modification Date:
2024-10-26 @ 3:25 PM
Study NCT ID:
NCT06335433
Status:
RECRUITING
Last Update Posted:
2024-03-28
First Post:
2024-03-21
Brief Title:
Isometric Handgrip Training Frequency and Blood Pressure in People With Hypertension
Sponsor:
Swansea University
Organization:
Swansea University
Study Overview
Official Title:
The Dose Response Effect of Isometric Handgrip Training Frequency on Blood Pressure and Vascular Health in People With Hypertension A Randomised Controlled Trial
Status:
RECRUITING
Status Verified Date:
2024-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Hypertension is the most important cause of cardiovascular disease CVD stroke and premature death WHO 2021 It is estimated by The World Health Organisation in 2021 that 14 billion individuals across the globe have high blood pressure with only 14 of people actively managing these elevated levels Simple and effective lifestyle strategies are required to help people improve their blood pressure andor attenuate increases in blood pressure with ageing Physical activity is one possible strategy in previous research several different types of physical activity have been shown to have beneficial effects on blood pressure Blackwell et al 2017 However many individuals do not adhere to currently recommended levels of physical activity 150 mins of moderate intensity physical activity per week due to a combination of the required time commitment lack of motivation and the associated levels of effort exertion and physical discomfort Korkiakangas et al 2009 Thus there is a need to identify alternative exercise interventions which will overcome these barriers but remain effective at improving blood pressure Herrod Lund Phillips 2021 Toohey et al 2018
Low intensity isometric hand grip exercise training IET has been shown to result in large decreases in resting blood pressure in younger and older age groups in both men and women and in individuals with normal as well as elevated baseline blood pressure Badrov et al 2013 Bentley et al 2018 Millar et al 2014 In this research IET has almost universally involved performing 4 x 2 IET holds at 30 of maximal voluntary contraction 3 times a week over a 4-8-week intervention Millar et al 2014 There are very few studies that have investigated the effect of changing different protocol parameters on changes in blood pressure and vascular health and the minimal effective dose of IET is unknown Defining the minimal effective dose of different types of exercise may help overcome key barriers to exercise by lowering the required time commitment reducing perceived effortexertion and promoting more positive affective responses One important modifiable parameter is training frequency and it is unknown whether reducing the frequency of IET will reduce the efficacy for improving blood pressure
Therefore the primary objective of this study is to determine if reducing the frequency of isometric handgrip training from four times a week to two times a week will affect the improvements in resting blood pressure and vascular health in people with hypertension A secondary objective is to investigate the acute affective and perceptual responses to sessions of IET and the effect of training on these acute affectiveperceptual responses
Low intensity isometric hand grip exercise training IET has been shown to result in large decreases in resting blood pressure in younger and older age groups in both men and women and in individuals with normal as well as elevated baseline blood pressure Badrov et al 2013 Bentley et al 2018 Millar et al 2014 In this research IET has almost universally involved performing 4 x 2 IET holds at 30 of maximal voluntary contraction 3 times a week over a 4-8-week intervention Millar et al 2014 There are very few studies that have investigated the effect of changing different protocol parameters on changes in blood pressure and vascular health and the minimal effective dose of IET is unknown Defining the minimal effective dose of different types of exercise may help overcome key barriers to exercise by lowering the required time commitment reducing perceived effortexertion and promoting more positive affective responses One important modifiable parameter is training frequency and it is unknown whether reducing the frequency of IET will reduce the efficacy for improving blood pressure
Therefore the primary objective of this study is to determine if reducing the frequency of isometric handgrip training from four times a week to two times a week will affect the improvements in resting blood pressure and vascular health in people with hypertension A secondary objective is to investigate the acute affective and perceptual responses to sessions of IET and the effect of training on these acute affectiveperceptual responses
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None