Ignite Creation Date:
2024-05-06 @ 8:19 PM
Last Modification Date:
2024-10-26 @ 3:24 PM
Study NCT ID:
NCT06330168
Status:
RECRUITING
Last Update Posted:
2024-03-28
First Post:
2024-03-19
Brief Title:
Paravertebral Calcitonin in Thoracotomy
Sponsor:
Tanta University
Organization:
Tanta University
Study Overview
Official Title:
The Analgesic Value of Paravertebral Calcitonin in Patients Undergoing Thoracotomy
Status:
RECRUITING
Status Verified Date:
2024-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This prospective randomized double-blinded controlled study will be conducted to evaluate the effect of adding calcitonin to bupivacaine in thoracic paravertebral block for patients undergoing thoracotomy
Detailed Description:
Single-shot thoracic paravertebral block combined with intravenous analgesia is one of the regional techniques used for controlling pain in patients undergoing thoracic surgery However few articles demonstrated its effects on acute pain and chronic pain after thoracotomy and revealed high postoperative opioid consumption and inability to reduce the incidence of chronic pain
Calcitonin has previously been shown to be effective in the management of acute pain following amputation vertebral fractures and other neuropathic conditions
Using calcitonin as an additive in thoracic paravertebral block was not evaluated in previous studies we conducted this study as we hypothesize that calcitonin use as an additive in thoracic paravertebral block for patients undergoing thoracotomy may have extended analgesic effects regarding decreasing postoperative pain scores opioid consumption and this value may decrease the incidence of chronic post-thoracotomy pain
In both groups ultrasound-guided thoracic paravertebral block will be performed before anesthetic induction using a high-frequency linear probe after identifying the paravertebral space of the proposed level of intercostal skin incisionGeneral anesthesia in both groups will be similar
Calcitonin has previously been shown to be effective in the management of acute pain following amputation vertebral fractures and other neuropathic conditions
Using calcitonin as an additive in thoracic paravertebral block was not evaluated in previous studies we conducted this study as we hypothesize that calcitonin use as an additive in thoracic paravertebral block for patients undergoing thoracotomy may have extended analgesic effects regarding decreasing postoperative pain scores opioid consumption and this value may decrease the incidence of chronic post-thoracotomy pain
In both groups ultrasound-guided thoracic paravertebral block will be performed before anesthetic induction using a high-frequency linear probe after identifying the paravertebral space of the proposed level of intercostal skin incisionGeneral anesthesia in both groups will be similar
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None