Ignite Creation Date:
2024-05-06 @ 8:19 PM
Last Modification Date:
2024-10-26 @ 3:25 PM
Study NCT ID:
NCT06336681
Status:
RECRUITING
Last Update Posted:
2024-03-29
First Post:
2024-03-07
Brief Title:
Inspiratory Muscle Training on The Severity of Exercise-Induced Bronchoconstriction and Time-Trial Performance IMT_EIB
Sponsor:
Indiana University
Organization:
Indiana University
Study Overview
Official Title:
Effect of Flow-Resistive Inspiratory Muscle Training on The Severity of Exercise-Induced Bronchoconstriction and Cycling Time-Trial Performance
Status:
RECRUITING
Status Verified Date:
2024-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
IMT_EIB
Brief Summary:
Due to the lack of studies examining the impact of inspiratory muscle training IMT on the severity of exercise-induced bronchoconstriction EIB and exercise performance the specific aim of this study is to assess the efficacy of flow-resistive IMT on EIB severity and symptoms short-acting beta-2-agonist medication use operating lung volumes respiratory and limb locomotor muscle deoxygenation during constant-load cycling exercise exertional dyspnea and cycling time-trial performance
Detailed Description:
To the investigators knowledge no study has been conducted assessing the impact of inspiratory muscle training IMT on exercise-induced bronchoconstriction EIB severity exertional dyspnea and cycling time-trial performance A review noted that studies examining the impact of IMT on asthma have all demonstrated an increase in inspiratory muscle strength maximal inspiratory pressure MIP and endurance sustained maximal inspiratory pressure In addition it has been observed that the reduction in the perception of dyspnea following and during exercise leads to a reduction in short-acting beta-2-agonist SABA use and fewer asthma symptoms The same review also noted the lack of data available to explain the impacts of IMT on exercise performance and tolerance in athletes with EIB Due to the lack of studies examining the impact of IMT on the severity of EIB and exercise performance the specific aim of this study is to assess the efficacy of flow-resistive IMT on EIB severity and symptoms SABA medication use operating lung volumes respiratory and limb locomotor muscle deoxygenation during constant-load cycling exercise femoral blood flow exertional dyspnea and cycling time-trial performance It is hypothesized that eight weeks of IMT will reduce EIBs severity and symptoms respiratory and limb locomotor muscle deoxygenation improve operating lung volumes and exertional dyspnea and improve cycling time-trial performance
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
True
Is an Unapproved Device?:
True
Is a PPSD?:
None
Is a US Export?:
True
Is an FDA AA801 Violation?:
None