Ignite Creation Date:
2024-05-06 @ 8:18 PM
Last Modification Date:
2024-10-26 @ 3:25 PM
Study NCT ID:
NCT06337227
Status:
RECRUITING
Last Update Posted:
2024-04-02
First Post:
2024-03-22
Brief Title:
Potential Role of Sirtuins as Epigenetic Biomarkers of the Patient With Atherosclerosis or Calcific Aortic Stenosis
Sponsor:
IRCCS SYNLAB SDN
Organization:
IRCCS SYNLAB SDN
Study Overview
Official Title:
Potential Role of Sirtuins as Epigenetic Biomarkers for the Clinical Management of the Patient With Atherosclerosis or Calcific Aortic Stenosis
Status:
RECRUITING
Status Verified Date:
2024-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The project aims to shed light on the role of Sirtuins enzymes belonging to the third class of histone deacetylases class III involved in epigenetic modifications deacetylation focusing mainly on Sirtuin 6 SIRT6 as a regulator of atherosclerosis and severe aortic valve stenosis through molecular-based and epigenetic studies in human VSMC cells
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None