Ignite Creation Date:
2024-05-06 @ 8:18 PM
Last Modification Date:
2024-10-26 @ 3:25 PM
Study NCT ID:
NCT06334549
Status:
RECRUITING
Last Update Posted:
2024-03-28
First Post:
2024-03-08
Brief Title:
A Prospective Study of Vasopressor on Cerebral Oxygenation During General Anesthesia
Sponsor:
Dalian Municipal Central Hospital
Organization:
Dalian Municipal Central Hospital
Study Overview
Official Title:
Effects of Vasopressor on Cerebral Oxygenation During General Anesthesia in Abdominal Surgery
Status:
RECRUITING
Status Verified Date:
2024-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is to investigate whether norepinephrineN phenylephrineP or ephedrineE have different effect on cerebral oxygenation in abdominal surgery with propofol or sevoflurane
Detailed Description:
This study was a single-center randomized double-blinded controlled trial First the effects of E P or N on cerebral oxygen saturationrScO2 under general anesthesia in abdominal surgery were studied Patients with abdominal surgery were evaluated using near-infrared spectroscopy Continual changes in systolic blood pressure SBP diastolic blood pressure DBP mean arterial blood pressure MAP heart rate HR stroke volume SV cardiac output CO and systemic vascular resistance SVR will be measured with LiDCO rapidV3 monitoring system To investigate the individualized therapeutic options specific mechanisms of the three vasopressors on rScO2 and CO
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None