Ignite Creation Date:
2024-05-06 @ 8:18 PM
Last Modification Date:
2024-10-26 @ 3:24 PM
Study NCT ID:
NCT06326632
Status:
COMPLETED
Last Update Posted:
2024-03-22
First Post:
2024-03-17
Brief Title:
Comparative Effectiveness Study of Constant-Load Versus Graded Aerobic Exercise in Obese Children With Bronchial Asthma
Sponsor:
Cairo University
Organization:
Cairo University
Study Overview
Official Title:
Constant-load Versus Graded Aerobic Exercise for Promoting Cardiorespiratory Fitness and Functional Capacity in Obese Children With Bronchial Asthma a Randomized Comparative Effectiveness Inquiry
Status:
COMPLETED
Status Verified Date:
2024-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study aimed to compare the effect of constant-load aerobic exercise CL-AE and graded aerobic exercise G-AE on cardiopulmonary fitness and functional capacity in a cohort of obese children with bronchial asthma BA
A total of 78 children with BA were randomly assigned to the CL-AE group n 26 who underwent moderate-intensity aerobic training with the training load maintained at the same level throughout the entire program besides the respiratory re-training program the G-AE group n 26 received an intensity- and duration-graded aerobic training in addition to the respiratory re-training program or the control group n 29 who only engaged in a respiratory re-training program Interventions were administered three timesweek for 12 successive weeks
The cardiopulmonary fitness and functional capacity were evaluated in the three groups before and after the completion of the assigned interventions
A total of 78 children with BA were randomly assigned to the CL-AE group n 26 who underwent moderate-intensity aerobic training with the training load maintained at the same level throughout the entire program besides the respiratory re-training program the G-AE group n 26 received an intensity- and duration-graded aerobic training in addition to the respiratory re-training program or the control group n 29 who only engaged in a respiratory re-training program Interventions were administered three timesweek for 12 successive weeks
The cardiopulmonary fitness and functional capacity were evaluated in the three groups before and after the completion of the assigned interventions
Detailed Description:
Seventy-eight children with BA were recruited from the Pulmonary MedicineCritical Care and Allergy-Immunology at King Khalid Hospital and two referral hospitals in Riyadh Saudi Arabia The study included children with moderate clinically stable BA aged 8-18 years had a body mass index between 30 to 35 kgm2 had no abnormalities of the lower limbs or spine maintained constant medication dosages in the past three months and did not engage in a regular exercise program in the past six months Children were excluded if they had exacerbated asthma symptoms chronic lung comorbidities and cardiovascular or musculoskeletal conditions expected to hinder the training
Outcome measures
Cardiopulmonary fitness The peak oxygen uptake was assessed through the McMaster cycling protocol
Functional Capacity The 6-minute walk test was used to assess the submaximal functional capacity Perceived dyspnea and fatigue Borgs category ratio scale CR-10 was used to explore how much dyspnea and fatigue they perceived after the 6-minute walk test
Interventions
The CL-AE group received a 12-week aerobic training three times in addition to the respiratory re-training the program included a moderate-intensity aerobic training program with an intensity set at 65 of the maximum age-predicted heart rate for 45 minutes The training intensity and duration were maintained at the same level throughout the program The CL-AE program included a warm-up for 5 minutes and a cool-down for 5 minutes
The G-AE group received a 12-week aerobic training three times in addition to the respiratory re-training The G-AE program commenced with a training intensity corresponding to 50 of the maximum age-predicted heart rate for 25 minutes in the first two weeks which progressed on a two-week basis and ended up with a training intensity corresponding to 75 of the maximum age-predicted heart rate for 50 minutes in the last two weeks The G-AE program also included a warm-up for 5 minutes and a cool-down for 5 minutes
The control group received the respiratory re-training only 30 minutes per session three times a week for 12 consecutive weeks The program consisted of diaphragmatic breathing exercises breath-hold and breathing control exercises pursed lip breathing respiratory muscle strengthening postural correction exercises and relaxation techniques
Outcome measures
Cardiopulmonary fitness The peak oxygen uptake was assessed through the McMaster cycling protocol
Functional Capacity The 6-minute walk test was used to assess the submaximal functional capacity Perceived dyspnea and fatigue Borgs category ratio scale CR-10 was used to explore how much dyspnea and fatigue they perceived after the 6-minute walk test
Interventions
The CL-AE group received a 12-week aerobic training three times in addition to the respiratory re-training the program included a moderate-intensity aerobic training program with an intensity set at 65 of the maximum age-predicted heart rate for 45 minutes The training intensity and duration were maintained at the same level throughout the program The CL-AE program included a warm-up for 5 minutes and a cool-down for 5 minutes
The G-AE group received a 12-week aerobic training three times in addition to the respiratory re-training The G-AE program commenced with a training intensity corresponding to 50 of the maximum age-predicted heart rate for 25 minutes in the first two weeks which progressed on a two-week basis and ended up with a training intensity corresponding to 75 of the maximum age-predicted heart rate for 50 minutes in the last two weeks The G-AE program also included a warm-up for 5 minutes and a cool-down for 5 minutes
The control group received the respiratory re-training only 30 minutes per session three times a week for 12 consecutive weeks The program consisted of diaphragmatic breathing exercises breath-hold and breathing control exercises pursed lip breathing respiratory muscle strengthening postural correction exercises and relaxation techniques
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None