Ignite Creation Date:
2024-05-06 @ 8:18 PM
Last Modification Date:
2024-10-26 @ 3:24 PM
Study NCT ID:
NCT06325527
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-03-22
First Post:
2024-02-26
Brief Title:
Cognitive Impairment Cohort Study of the Elderly Population in YuGarden
Sponsor:
Ruijin Hospital
Organization:
Ruijin Hospital
Study Overview
Official Title:
Shanghai Cognitive Impairment Study of the Elderly Population YuGarden Cohort
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The goal of this prospective observational research with an 8-year follow-up is to study the cognitive changes in the elderly in YuGarden community Shanghai China
The main questions it aims to answer are
incidence of cognitive impairment in community converting to mild cognitive impairment or Alzheimers disease
to build a predictive model for the progression of cognitive impairment
The main questions it aims to answer are
incidence of cognitive impairment in community converting to mild cognitive impairment or Alzheimers disease
to build a predictive model for the progression of cognitive impairment
Detailed Description:
This study is a prospective observational study which involves a large sample cohort of the elderly aged 60 to 85 years in YuGarden community Shanghai China with an 8-year follow-up Demographic information peripheral organs evaluation facial expression hearing OCT angiography cognitive tests MMSE ADL biospecimen peripheral blood urine feces gingival crevicular fluid speech information neuroimaging MRI PET and electroencephalogram EEG will be collected and analyzed Follow-up visits will be conducted twice a year for 4 visits and each visit includes cognitive tests biospecimen collection speech test MRI and EEG The primary outcome is the incidence of cognitive impairment indicating people who convert to mild cognitive impairment MCI or Alzheimers disease AD Furthermore a predictive model for the progression of cognitive impairment will be constructed
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None