Ignite Creation Date:
2024-05-06 @ 8:18 PM
Last Modification Date:
2024-10-26 @ 3:24 PM
Study NCT ID:
NCT06323811
Status:
RECRUITING
Last Update Posted:
2024-03-21
First Post:
2024-03-06
Brief Title:
Comparison of Free-breathing 3D Quantitative Perfusion in Patients With MINOCA and MINOCA-mimics
Sponsor:
University of Zurich
Organization:
University of Zurich
Study Overview
Official Title:
Comparison of Free-breathing 3D Quantitative Perfusion in Patients With MINOCA Tako-Tsubo SCAD Myocarditis and NSTEMI in the Acute Phase and Post Convalescence
Status:
RECRUITING
Status Verified Date:
2024-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
COPE-CMR
Brief Summary:
This clinical study examines patients presenting with acute myocardial infarction and no significant coronary artery disease on coronary angiography MINOCA and patients with MINOCA-mimics with advanced CMR
The present study aims to
assess the microvascular function with a novel quantitative 3D myocardial perfusion imaging approach in the acute phase and post-convalescence
refine the role and diagnostic potential of advanced quantitative CMR imaging
assess the potential prognostic significance of microvascular dysfunction and epicardial adipose tissue on cardiovascular outcomes
Participants will undergo advanced CMR imaging in the acute setting within 10 days after event and post convalescence after 3 months
The present study aims to
assess the microvascular function with a novel quantitative 3D myocardial perfusion imaging approach in the acute phase and post-convalescence
refine the role and diagnostic potential of advanced quantitative CMR imaging
assess the potential prognostic significance of microvascular dysfunction and epicardial adipose tissue on cardiovascular outcomes
Participants will undergo advanced CMR imaging in the acute setting within 10 days after event and post convalescence after 3 months
Detailed Description:
Advanced CMR includes a novel free-breathing motion-informed locally low-rank quantitative 3D myocardial perfusion imaging Perfusion imaging will be compared with 3D late gadolinium enhancement LGE imaging A cine Dixon sequence is performed for the assessment of epicardial adipose tissue EAT
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None