Ignite Creation Date:
2024-05-06 @ 8:16 PM
Last Modification Date:
2024-10-26 @ 3:24 PM
Study NCT ID:
NCT06326762
Status:
COMPLETED
Last Update Posted:
2024-03-22
First Post:
2024-03-03
Brief Title:
Gap CO2 in Septic Patient to Predict Cardiomyopathy Septic
Sponsor:
Mohammed VI University Hospital
Organization:
Mohammed VI University Hospital
Study Overview
Official Title:
Gap CO2 in Septic Patient to Predict Cardiomyopathy Septic
Status:
COMPLETED
Status Verified Date:
2024-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
the investigators included 98 patients admitted for sepsis and septic shock 684 men 316 women with an average age of 6042 years 1513 ranging from 21 to 96 years The average length of hospital stay was 753 days The most noted medical histories were diabetes 388 hypertension 286 and renal insufficiency 171 Regarding laboratory findings the mean white blood cell count was 1598516 cellsmm³ the mean C-reactive protein CRP level was 22769 mgL and the mean procalcitonin level was 5043 µgL In terms of blood gas analysis the mean lactate level was 367 mmolL and the mean PCO2 gap DELTAPCO2 was 485 All our patients were continuously monitored by pulse wave analysis the mean cardiac output was 569 Lmin and the mean cardiac index was 414 Lsm² All our patients underwent an echocardiogram which is a routine examination in our department and is performed at the patients bedside The average left ventricular ejection fraction LVEF was 5173 and the average subaortic peak velocity ITV was 1466 cm
Subsequently the investigators examined the clinical and paraclinical profile of patients with septic cardiomyopathy the investigators identified 19 patients with this condition while 79 patients did not exhibit cardiac involvement The percentage was significantly higher in the population with cardiac involvement accounting for 283 Among the patients with cardiac involvement 765 had a PCO2 gap DELTAPCO2 6 mmHg a significantly reduced cardiac output with an average of 33 Lmin and a predominantly low cardiac index with 643 having an index 22 Lminm² The mortality rate was significantly increased at 737
Subsequently the investigators examined the clinical and paraclinical profile of patients with septic cardiomyopathy the investigators identified 19 patients with this condition while 79 patients did not exhibit cardiac involvement The percentage was significantly higher in the population with cardiac involvement accounting for 283 Among the patients with cardiac involvement 765 had a PCO2 gap DELTAPCO2 6 mmHg a significantly reduced cardiac output with an average of 33 Lmin and a predominantly low cardiac index with 643 having an index 22 Lminm² The mortality rate was significantly increased at 737
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None