Ignite Creation Date:
2024-05-06 @ 8:16 PM
Last Modification Date:
2024-10-26 @ 3:24 PM
Study NCT ID:
NCT06323018
Status:
RECRUITING
Last Update Posted:
2024-04-04
First Post:
2024-03-13
Brief Title:
Effects of Remote Ischaemic Preconditioning in Cemented Hip Arthroplasty
Sponsor:
University of Tartu
Organization:
University of Tartu
Study Overview
Official Title:
Effects of Remote Ischaemic Preconditioning in Cemented Total Hip Arthroplasty Randomized Controlled Trial
Status:
RECRUITING
Status Verified Date:
2024-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
PRINCIPAL
Brief Summary:
Total joint arthroplasty is one of the best treatment options for end-stage osteoarthritis Cemented hip arthroplasty is mainly indicated for elderly patients with poor bone quality and multiple comorbidities Bone cement implantation syndrome is associated with cemented hip arthroplasty and it has been shown to increase cardiovascular and renal complication and brain damage postoperatively The aim of this project is to elucidate whether remote-ischemic preconditioning RIPC has multi-organ protective effect in cemented hip arthroplasty patients
Detailed Description:
Total joint arthroplasty is one of the best treatment options for end-stage osteoarthritis Cemented hip arthroplasty is mainly indicated for elderly patients with poor bone quality and multiple comorbidities Cemented hip arthroplasty is strongly associated with bone cement implantation syndrome BCIS It is characterized by hypoxia hypotension andor unexpected loss of consciousness occurring around the time of cementation prosthesis insertion or reduction of the joint It has been shown to increase cardiovascular and renal complication and brain damage postoperatively Remote-ischemic preconditioning has shown kidney myocardial and brain injury protective effect on non-cardiac surgery patients The aim of this project is to elucidate whether remote-ischemic preconditioning RIPC has multi-organ protective effect in cemented hip arthroplasty patients
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None