Ignite Creation Date:
2024-05-06 @ 8:16 PM
Last Modification Date:
2024-10-26 @ 3:24 PM
Study NCT ID:
NCT06317753
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-03-22
First Post:
2024-03-02
Brief Title:
Can Exercise Rewire the Brain Addiction Circuitry
Sponsor:
University of Minho
Organization:
University of Minho
Study Overview
Official Title:
Can Exercise Rewire the Brain Addiction Circuitry A Randomized Trial of Exercise and Binge Drinking
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
REWIRED
Brief Summary:
The aim of the present study is to apply neuroimaging techniques to investigate how physical exercise may influence the addiction circuitry ultimately reducing alcohol consumption and craving in youth binge drinkers This proposal will advance knowledge on how exercise may modulate the neurocircuitry of addiction Uncovering the neurobiological mechanisms underlying the interactive neural effects of exercise and alcohol intake may provide additional scientific insights for the development of preventive and intervention programs for youth BD and AUD
Detailed Description:
The proposed research plan focuses on the identification of changes in the structural and functional brain parameters eg volume brain activity in response to a physical exercise PE protocol on the neurocircuitry of addiction after a 4 month-intervention program in college binge drinkers BDs The main objectives of this proposal are O1 to evaluate the potential benefits of PE on the brain structure and function particularly in the neurocircuitry of addiction in a sample of Portuguese college students with a binge drinking pattern of alcohol use and O2 to determine whether the PE intervention reduces craving and alcohol consumption levels in BDs The present project will involve i a pre-intervention comprehensive evaluation of behavioral alcohol consumption psychological craving levels physiological VO2 HRV and neurological neuroimaging variables ii a training phase consisting of 48 sessions 3 weekly sessions16 weeks of aerobic exp group 1 agility-cognitive exp group 2 exercise and stretching control group iii a post-intervention evaluation of behavioral physiological and neurological neuroimaging variables iv and a 6 months follow- up evaluation of behavioral physiologicaln and cognitive variables A randomized controlled trial will be implemented at the University of Minho It will include a total of 60 college students with a binge drinking pattern of alcohol intake 20 participants per condition
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None