Ignite Creation Date:
2024-05-06 @ 8:15 PM
Last Modification Date:
2024-10-26 @ 3:24 PM
Study NCT ID:
NCT06316609
Status:
ACTIVE_NOT_RECRUITING
Last Update Posted:
2024-03-18
First Post:
2024-02-27
Brief Title:
Prenatal Exposure to Emerging Contaminants and Childrens Atopic Dermatitis
Sponsor:
Childrens Hospital of Fudan University
Organization:
Childrens Hospital of Fudan University
Study Overview
Official Title:
Prenatal Exposure to Emerging Contaminants and Offsprings Atopic Dermatitis PECCAD
Status:
ACTIVE_NOT_RECRUITING
Status Verified Date:
2024-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
PECCAD
Brief Summary:
This prospective cohort study aims to investigate the association between prenatal blood levels of Emerging Contaminants and the five-year incidence of atopic dermatitis AD in offspring
Detailed Description:
This prospective birth cohort study conducted within the Shanghai prenatal population involves the collection of maternal blood samples during gestation to directly measure the biological exposure levels of Emerging Contaminants including Per- and Polyfluoroalkyl Substances PFAS Organophosphate Flame Retardants OPFRs and Microplastics Serum and whole blood levels of these contaminants are evaluated during pregnancy at 12-14 22-26 and 31-34 gestational weeks Subsequently the study assesses skin barrier function in infants at 24-48 hours 42 days and 6 months of age During a five-year period the occurrence of atopic dermatitis AD in offspring is assessed The objectives of this cohort study are twofold 1 to elucidate the relationship between maternal exposure to Emerging Contaminants and the development of AD in offspring and 2 to evaluate the impact of such exposure on the skin barrier function of infants This research aims to provide substantial evidence for the prevention of AD offering a unique and meaningful approach to mitigating the incidence of AD
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None