Ignite Creation Date:
2024-05-06 @ 8:14 PM
Last Modification Date:
2024-10-26 @ 3:23 PM
Study NCT ID:
NCT06300788
Status:
RECRUITING
Last Update Posted:
2024-07-08
First Post:
2024-02-13
Brief Title:
Inorganic Pyrophosphate Homeostasis PPi in Pediatric Chronic Kidney Disease
Sponsor:
Centre Hospitalier Universitaire de Nice
Organization:
Centre Hospitalier Universitaire de Nice
Study Overview
Official Title:
Inorganic Pyrophosphate Homeostasis PPi in Pediatric Chronic Kidney Disease - PPi-DIA
Status:
RECRUITING
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
PPi-DIA
Brief Summary:
The investigator aim to identify the role of inorganic pyrophosphate and other anti-calcifying molecules in vascular disease in children with chronic kidney disease with a view to developing therapeutic approaches aimed at limiting the onset of vasculopathy
Detailed Description:
The study of pro- and anti-calcifying molecules in children with chronic kidney disease will be carried out using dosages made on serum in comparison with the dosage of these same molecules in control children matched according to age and sex without chronic kidney disease An evaluation of vascular function by clinical auscultation palpation and ultrasound techniques measurement of intima-media thickness and measurement of pulse wave velocity will also be carried out in children with chronic kidney disease and compared to norms of children without chronic kidney disease These evaluations aim to improve understanding of the pathophysiology of vascular calcification and thus open up therapeutic perspectives in these children
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None