Ignite Creation Date:
2024-05-06 @ 8:14 PM
Last Modification Date:
2024-10-26 @ 3:23 PM
Study NCT ID:
NCT06309459
Status:
COMPLETED
Last Update Posted:
2024-03-13
First Post:
2024-01-10
Brief Title:
Carbonic Anhydrase IX Enzyme in Triple Negative Breast Carcinoma
Sponsor:
Kahramanmaras Sutcu Imam University
Organization:
Kahramanmaras Sutcu Imam University
Study Overview
Official Title:
Carbonic Anhydrase IX Enzyme in Triple Negative Breast Carcinoma Relationship With Prognostic Factors and Response to Neoadjuvant Chemotherapy
Status:
COMPLETED
Status Verified Date:
2024-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Triple-negative breast carcinoma is characterized by the absence of estrogen receptors progesterone receptors and HER2neu receptors Carbonic anhydrase IX CA IX is a tumor-associated cell surface glycoprotein that is involved in adaptation to hypoxia-induced acidosis and plays a role in cancer progression This study aimed to investigate CA IX expression in TNBC and its relationship with treatment effect
Detailed Description:
Tru-cut biopsy materials sent to our hospital pathology laboratory between August 2018 and May 2023 will be examined Invasive carcinoma cases will be evaluated according to estrogen progesterone and HER 2 receptor levels Triple-negative tumor cases were isolated and those cases who underwent breast resection in our hospital after receiving neoadjuvant chemotherapy Adriamycin cyclophosphamide and then paclitaxel for 4 cycles were included in the study
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None