Ignite Creation Date:
2024-05-06 @ 8:13 PM
Last Modification Date:
2024-10-26 @ 3:22 PM
Study NCT ID:
NCT06294808
Status:
COMPLETED
Last Update Posted:
2024-03-06
First Post:
2024-02-26
Brief Title:
Predicting Survival After Surgical Resection for the Entire Spectrum of Anatomically Resectable HCC
Sponsor:
National Cancer Centre Singapore
Organization:
National Cancer Centre Singapore
Study Overview
Official Title:
Predicting Survival After Surgical Resection for the Entire Spectrum of Anatomically Resectable HCC a Metroticket Approach
Status:
COMPLETED
Status Verified Date:
2024-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Clinical outcomes after surgical resection in HCC is a continuum and is clearly related to tumor burden but needs better definition The researchers describe the use of the metro ticket approach to analyze surgical outcomes over the whole spectrum of anatomically resectable HCC to define overall survival including intermediate stage tumors BCLC B The analysis the researchers provide in this study enables the clinician to select the optimal surgical resection candidate based on robust long term survival data
In addition study compares outcome for open surgery vs laparoscopic surgery survival outcome for viral and non-viral HCC using Albumin-Bilirubin ALBI for more comprehensive study result
In addition study compares outcome for open surgery vs laparoscopic surgery survival outcome for viral and non-viral HCC using Albumin-Bilirubin ALBI for more comprehensive study result
Detailed Description:
Patients who underwent surgical resection both open surgery and laparoscopic surgery for HCC from 1st January 2000 to 30th June 2018 by the joint hepato-pancreato-biliary surgery service at the Singapore Healthcare Group of Hospitals Singapore General Hospital and the National Cancer Centre Singapore were retrospectively identified from a prospectively kept institutional database
The assessment of the size number of nodules and vascular invasion of HCC were based on pre-operative CTMRI imaging and pathological assessment of the resected specimens All resections were histologically confirmed as HCC Patients with macrovascular invasion and extrahepatic invasion were excluded from analysis as were patients resected for other palliative intents eg ruptured HCC
The assessment of the size number of nodules and vascular invasion of HCC were based on pre-operative CTMRI imaging and pathological assessment of the resected specimens All resections were histologically confirmed as HCC Patients with macrovascular invasion and extrahepatic invasion were excluded from analysis as were patients resected for other palliative intents eg ruptured HCC
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None