Ignite Creation Date:
2024-05-06 @ 8:13 PM
Last Modification Date:
2024-10-26 @ 3:22 PM
Study NCT ID:
NCT06292494
Status:
RECRUITING
Last Update Posted:
2024-03-05
First Post:
2023-12-10
Brief Title:
Focused Ultrasound for Drug-resistant Epilepsy
Sponsor:
Taipei Veterans General Hospital Taiwan
Organization:
Taipei Veterans General Hospital Taiwan
Study Overview
Official Title:
Focused Ultrasound for Drug-resistant Epilepsy
Status:
RECRUITING
Status Verified Date:
2024-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Focused ultrasound FUS has been shown to differentially lesion or modulate excite and inhibit brain circuit and neural activity across a broad range of acoustic stimulus parameters intensity duty cycle pulse repetition frequency and pulse duration for decades From our previous study FUS sonication may suppress the number of epileptic signal bursts observed in EEG recordings after the induction of acute epilepsy The presence of the suppressive effect was found in terms of the number of epileptic EEG spikes from the analysis of the unfiltered and theta-band EEG activity and further discontinue the seizure attacks EEG activity has also been consistently reported to have a positive correlation with the level of epilepsy and FUS-mediated reduction of epileptic EEG activity was most notably observed no matter lesioning or modulating effects The aims of this study are to demonstrate the safety and efficacy of FUS technology in epilepsy patients and to estimate the optimal parameters of focused ultrasound exposure that will be used in the case of epilepsy
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None