Ignite Creation Date:
2024-05-06 @ 8:13 PM
Last Modification Date:
2024-10-26 @ 3:23 PM
Study NCT ID:
NCT06298682
Status:
RECRUITING
Last Update Posted:
2024-03-12
First Post:
2024-03-01
Brief Title:
Characterization of Exosomes Platelets-released
Sponsor:
Centro Cardiologico Monzino
Organization:
Centro Cardiologico Monzino
Study Overview
Official Title:
Characterization of Exosomes Platelets-released
Status:
RECRUITING
Status Verified Date:
2024-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
EXOPLT
Brief Summary:
Extracellular vesicles EVs play a key role in cell-to-cell communication They are small vesicles that contain rich molecular cargo Recently they have been proposed as biomarkers for clinical diagnostics EVs include three classes small EVs exosomes large EVs microparticles and apoptotic bodies Platelet-derived EVs PEVs are the most abundant class in human blood and can actively participate in numerous physiological and pathological processes The information about the role of platelet exosomes in cardiovascular disease and the effect of antiplatelet agents on their release and content is very limited
Detailed Description:
This study is a multicentre observational We plan to enrol 54 subjects from Centro Cardiologico Monzino IRCCS and 121 buffy coat related to 121 subjects from Centro Trasfusionale Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico biographical and anthropomorphic data will be recorded a fasting blood venous sample from ante-cubital vein will be collected for the haematochemical analyses and for research samples
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None