Ignite Creation Date:
2024-05-06 @ 8:12 PM
Last Modification Date:
2024-10-26 @ 3:22 PM
Study NCT ID:
NCT06294119
Status:
RECRUITING
Last Update Posted:
2024-03-05
First Post:
2024-02-27
Brief Title:
Multivariate Approach to the Numerical Assessment of Cortical - Autonomic - VAscular Dynamic Interplay
Sponsor:
IRCCS Policlinico S Donato
Organization:
IRCCS Policlinico S Donato
Study Overview
Official Title:
Multivariate Approach to the Numerical Assessment of Cortical - Autonomic - VAscular Dynamic Interplay
Status:
RECRUITING
Status Verified Date:
2024-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
MANCAVA sets out fundamental methodologies for characterizing human fundamental physiological system interactions at a whole-body level particularly focusing on the interplay among cortical brain activity autonomic function and cerebrovascular autoregulatory mechanisms By investigating the complex time-varying mechanisms underlying the multisystem dynamic interactions novel methods linking various brain areas and reflex functions to target organs and districts such as heart and circulatory system are proposed with the clinical aim linked to the emerging topic of depression
In this scenario proper new mathematical tools will allow a significant leap from the current state of the art paving the way towards a new understanding of leading comorbid contributors to global diseases such as cardiac and cerebrovascular morbidity in mood disorders In turn this will provide an integration among physiological and psychological dimensions for a more holistic view on depression
Researchers professionals and patients will all benefit from a comprehensive assessment of brain-mind-body interplay leading to the new extended definition of default modemood network neurovascular-evoked responses to autonomic stimuli brain-autonomic consequences of emotional responses and physiological substrates of depressive states
In this scenario proper new mathematical tools will allow a significant leap from the current state of the art paving the way towards a new understanding of leading comorbid contributors to global diseases such as cardiac and cerebrovascular morbidity in mood disorders In turn this will provide an integration among physiological and psychological dimensions for a more holistic view on depression
Researchers professionals and patients will all benefit from a comprehensive assessment of brain-mind-body interplay leading to the new extended definition of default modemood network neurovascular-evoked responses to autonomic stimuli brain-autonomic consequences of emotional responses and physiological substrates of depressive states
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 2022SLB5MX | OTHER_GRANT | Italian Ministry of Research | None |