Ignite Creation Date:
2024-05-06 @ 8:12 PM
Last Modification Date:
2024-10-26 @ 3:23 PM
Study NCT ID:
NCT06298825
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-03-12
First Post:
2024-03-01
Brief Title:
S-ADHFSarcopenia in Patients With ADHF
Sponsor:
Guangdong Provincial Peoples Hospital
Organization:
Guangdong Provincial Peoples Hospital
Study Overview
Official Title:
Effect of Sarcopenia on Prognosis of Patients With Acute Decompensated Heart Failure a Prospective Multi-center Observational Cohort Study
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-01
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
S-ADHF
Brief Summary:
This is a prospective multi-center investigator-initiated observational cohort study Enrollment with a minimum of of 195 cases each for patients with and without sarcopenia Each patient is followed up for 6 month 1 year 2 years or until the occurrence of deathThis study will examine the correlation between sarcopenia and prognosis in different subgroups of patients and explore the additive effect of different comorbidities and sarcopenia on prognosis in patients with acute decompensated heart failure
Detailed Description:
Guangdong Provincial Peoples Hospital will be the lead center with an additional 4 hospitals designated as satellite centers for the study Enrollment of up to 500 participants adults aged over 18 years hospitalized for ADHF is planned with a minimum of of 195 cases each for patients with and without sarcopenia The sympathetic nervous activity psychosocial factors quality of life physical function and baseline physical activity will also be observed and recorded at baseline Each patient is followed up for 6 month 1 year 2 years or until the occurrence of death The primary clinical outcome is all-cause mortality at 6 months Other clinical outcomes of interest include cardiovascular mortality all-cause hospitalisation HF hospitalisation the frequency and length of hospitalization of patient readmitted and survival time from enrollment to death of deceased patients
This study will examine the correlation between sarcopenia and prognosis in different subgroups of patients and explore the additive effect of different comorbidities and sarcopenia on prognosis in patients with acute decompensated heart failure S-ADHF will provide important information and evidence on the clinical aspects of sarcopenia in patients with ADHF and will potentially and contribute to accurate risk stratification and optimal clinical management for patient with ADHF
This study will examine the correlation between sarcopenia and prognosis in different subgroups of patients and explore the additive effect of different comorbidities and sarcopenia on prognosis in patients with acute decompensated heart failure S-ADHF will provide important information and evidence on the clinical aspects of sarcopenia in patients with ADHF and will potentially and contribute to accurate risk stratification and optimal clinical management for patient with ADHF
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None