Ignite Creation Date:
2024-05-06 @ 8:12 PM
Last Modification Date:
2024-10-26 @ 3:22 PM
Study NCT ID:
NCT06295562
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-03-07
First Post:
2024-02-16
Brief Title:
Pharmacological Treatment Targeting Endotypic Traits of Obstructive Sleep Apnea
Sponsor:
China Medical University Hospital
Organization:
China Medical University Hospital
Study Overview
Official Title:
Pharmacological Treatment Targeting Endotypic Traits of Obstructive Sleep Apnea
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study will conduct 3 intervention trials with 44 different participants in each trial with 22 participants will undergo in-laboratory overnight polysomnograms PSGs at one night of medication intervention and the other 22 at taking placebo contained starch 1 h before sleep Three medication regimens will be tested 1 atomoxetine 80mg combined with oxybutynin 5mg 2 venlafaxine 375mg and 3 atomoxetine 80mg combined with trazodone 100mg Endotypic traits will be estimated using the Phenotyping Using Polysomnography method The primary outcome is the change in apnea-hypopnea index and secondary outcomes include endotypic traits and sleep parameters
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None