Ignite Creation Date:
2024-05-06 @ 8:12 PM
Last Modification Date:
2024-10-26 @ 3:22 PM
Study NCT ID:
NCT06284668
Status:
RECRUITING
Last Update Posted:
2024-03-05
First Post:
2024-02-01
Brief Title:
Esketamine vs Remimazolam for Postoperative Sleep Disturbance and Anxiety
Sponsor:
Tianjin Medical University General Hospital
Organization:
Tianjin Medical University General Hospital
Study Overview
Official Title:
Esketamine vs Remimazolam for Postoperative Sleep Disturbance and Anxiety in Patients Undergoing Oocyte Retrieval
Status:
RECRUITING
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To explore and compare the effects of esketamine and remimazolam on postoperative sleep disturbance in patients undergoing oocyte retrieval
Detailed Description:
Postoperative sleep disturbance PSD occur in the form of sleep deprivation circadian rhythm disturbance and structural abnormalities and have a high incidence in patients undergoing surgery Postoperative sleep disorders can lead to postoperative delirium and cognitive dysfunction aggravate postoperative acute pain and delay postoperative recovery
Benzodiazepines have a certain sedative hypnotic anti-anxiety effect and remimazolam as a new benzodiazepine its sedative hypnotic anti-anxiety effect is worthy of further exploration Esketamine is an N-methyl-D-aspartateNMDA receptor antagonist with analgesic and sedative effects and is widely used in clinical treatment of refractory depression For patients undergoing surgery in addition to sedation and analgesia whether the intraoperative use of esketamine has positive effects on postoperative sleep disturbance is worth exploring
Benzodiazepines have a certain sedative hypnotic anti-anxiety effect and remimazolam as a new benzodiazepine its sedative hypnotic anti-anxiety effect is worthy of further exploration Esketamine is an N-methyl-D-aspartateNMDA receptor antagonist with analgesic and sedative effects and is widely used in clinical treatment of refractory depression For patients undergoing surgery in addition to sedation and analgesia whether the intraoperative use of esketamine has positive effects on postoperative sleep disturbance is worth exploring
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None