Ignite Creation Date:
2024-05-06 @ 8:10 PM
Last Modification Date:
2024-10-26 @ 3:22 PM
Study NCT ID:
NCT06288828
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-03-01
First Post:
2024-02-22
Brief Title:
The Efficacy of Aerobic Exercise Training on Autonomic Nervous System and Endothelial Function in Patients With Compensated Cirrhosis
Sponsor:
King Chulalongkorn Memorial Hospital
Organization:
King Chulalongkorn Memorial Hospital
Study Overview
Official Title:
The Efficacy Of Aerobic Exercise Training On Autonomic Nervous System And Endothelial Function In Patients With Compensated Cirrhosis A Parallel Randomized Controlled Trial
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The goal of this clinical trial is to explore the impact of a 16-week aerobic exercise regimen on the autonomic nervous system and endothelial function in patients with compensated cirrhosis who maintain sedentary lifestyles The primary research question is
1 What effect does 16 weeks of aerobic exercise have on changes in the autonomic nervous system and endothelial function in cirrhotic patients
Additionally the secondary research questions are
1 How does a 16-week aerobic exercise program influence changes in muscle mass muscle strength and physical performance in cirrhotic patients
2 Is there a correlation between muscle mass and parameters of the autonomic nervous system in cirrhotic patients
Participants in the intervention group will undergo 150 minutes of moderate aerobic exercise per week for 16 weeks accompanied by a personalized nutritional plan 12 grams of protein per kilogram of ideal body weight per day and a calorie intake of 35 kilocalories per kilogram of ideal body weight per day The control group will solely receive nutritional guidance and maintain their sedentary lifestyle The researchers will compare outcomes between these two groups
1 What effect does 16 weeks of aerobic exercise have on changes in the autonomic nervous system and endothelial function in cirrhotic patients
Additionally the secondary research questions are
1 How does a 16-week aerobic exercise program influence changes in muscle mass muscle strength and physical performance in cirrhotic patients
2 Is there a correlation between muscle mass and parameters of the autonomic nervous system in cirrhotic patients
Participants in the intervention group will undergo 150 minutes of moderate aerobic exercise per week for 16 weeks accompanied by a personalized nutritional plan 12 grams of protein per kilogram of ideal body weight per day and a calorie intake of 35 kilocalories per kilogram of ideal body weight per day The control group will solely receive nutritional guidance and maintain their sedentary lifestyle The researchers will compare outcomes between these two groups
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None