Ignite Creation Date:
2024-05-06 @ 8:10 PM
Last Modification Date:
2024-10-26 @ 3:21 PM
Study NCT ID:
NCT06272331
Status:
COMPLETED
Last Update Posted:
2024-02-22
First Post:
2024-02-09
Brief Title:
Milk and Plant Protein Digestion
Sponsor:
Wageningen University
Organization:
Wageningen University
Study Overview
Official Title:
Postprandial Amino Acid Profiles and Gastric Protein Coagulation After Consumption of Milk and Plant-based Alternatives an Exploratory Study
Status:
COMPLETED
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
MAPP-D
Brief Summary:
The goal of this study is to explore the effect of protein quantity and quality in plant-based drinks Healthy normal-weight males aged between 18 and 45 years will be included in the study
The main objectives are to examine the differences in postprandial amino acid profiles and to examine differences in gastric behavior between cows milk and plant based drinks
Participants will visit after an overnight fast three times and have blood draws before and after consumption one of the study drinks There will be MRI scans of the stomach before and after consumption of the drink to assess gastric behavior
The main objectives are to examine the differences in postprandial amino acid profiles and to examine differences in gastric behavior between cows milk and plant based drinks
Participants will visit after an overnight fast three times and have blood draws before and after consumption one of the study drinks There will be MRI scans of the stomach before and after consumption of the drink to assess gastric behavior
Detailed Description:
Rationale There is a growing interest in plant-based alternatives for bovine milk However these plant-based drinks are not a complete nutritional substitute for bovine milk especially when focusing on the protein content and quality of these products Knowledge on the effects of protein quantity and quality of plant based drinks on postprandial plasma responses and gastric behavior compared to bovine milk is lacking
Objective To explore the effect of protein quantity and quality of protein in plant-based drinks In addition gastric behavior will be examined and compared to that of bovine milk
Study design Single-blind randomized cross-over study with three treatments
Study population 12 healthy normal-weight males aged 18-45 y
Intervention After an overnight fast participants will drink cows milk or a plant-based drink Gastric behavior will be monitored using Magnetic Resonance Imaging MRI Blood samples will be collected for plasma metabolomic analyses In addition wellbeing will be assessed
Objective To explore the effect of protein quantity and quality of protein in plant-based drinks In addition gastric behavior will be examined and compared to that of bovine milk
Study design Single-blind randomized cross-over study with three treatments
Study population 12 healthy normal-weight males aged 18-45 y
Intervention After an overnight fast participants will drink cows milk or a plant-based drink Gastric behavior will be monitored using Magnetic Resonance Imaging MRI Blood samples will be collected for plasma metabolomic analyses In addition wellbeing will be assessed
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None