Ignite Creation Date:
2024-05-06 @ 8:08 PM
Last Modification Date:
2024-10-26 @ 3:21 PM
Study NCT ID:
NCT06260501
Status:
COMPLETED
Last Update Posted:
2024-02-15
First Post:
2024-02-05
Brief Title:
Wetting Solution-ideal Body Weight Ratio in Liposuction Procedures
Sponsor:
Acibadem University
Organization:
Acibadem University
Study Overview
Official Title:
The Relationship Between Postoperative Complications and Wetting Solution-ideal Body Weight Ratio in Liposuction Procedures
Status:
COMPLETED
Status Verified Date:
2024-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Although the use of wetting solutions during high-volume liposuction is a standard approach it is unclear how to optimize wetting solutions and components and their effect on postoperative complications Since the super-wet technique aspiration of 1 cc per 1 cc of infiltrate was introduced in 1986 it has become one of the most frequently applied techniques worldwide Adrenaline and lidocaine are often added to WS due to their hemostatic and analgesic effects One of the major advantages of super-wet technique is that blood loss is quite low However potential cardiovascular side effects of WS and the amounts of epinephrine and lidocaine they contain such as volume overload local anesthetic toxicity hypertension arrhythmia and tachycardia are still a scoop of investigation In this study we examined the WS and the medications it contains from a different perspective to understand the possible cause of these adverse outcomes Despite the most suitable candidates for liposuction are patients with a BMI30 kgm2 and low comorbidity and age the patient group undergoing liposuction is often obese and overweight individuals require that obesity-related pathophysiological changes be taken into consideration Therefore we analyzed the patients by dividing them into two groups according to the amount of WS applied according to their IBW WSIBW90mlkg group I and WSIBW90mlkg group I In this study we aimed to evaluate the effect of wetting solutions and components calculated according to ideal body weight IBW on postoperative complications
Detailed Description:
Liposuction is one of the most popular aesthetic surgical procedures worldwide making it possible to remove a significant amount of adipose tissue Generally liposuction is seen as a benign minor operation but it can be considered a major surgery due to risk factors such as long operation times intraoperative volume shifts hypothermia usage of high-dose adrenaline and lidocaine in wetting solution WS and possibly cardiac or pulmonary fatal complications Therefore anesthesiologists and plastic surgeons need to be aware of the intraoperative and postoperative pathophysiological changes caused by liposuction In the literature large-volume liposuction is defined as the removal of more than 5 liters of lipoaspirate in a single procedure
The most suitable candidates for liposuction are individuals with BMI30 kgm2 but large-volume liposuction is applied more frequently to overweight and obese individuals However obesity can cause pathophysiological changes In particular increased cardiac output and changes in distribution volume may affect the pharmacokinetics and pharmacodynamics of drugs Medications administered according to actual body weight ABW may lead to adverse outcomes due to overdose For this reason some approaches recommend adjusting perioperative medications according to IBW instead of ABW The effects of WS and its components used in liposuction on patient outcomes have been examined in many studies but the IBWs of the patients have not been taken into consideration This study aimed to examine the effect of WSs calculated according to the IBW on postoperative complications and adverse events
The most suitable candidates for liposuction are individuals with BMI30 kgm2 but large-volume liposuction is applied more frequently to overweight and obese individuals However obesity can cause pathophysiological changes In particular increased cardiac output and changes in distribution volume may affect the pharmacokinetics and pharmacodynamics of drugs Medications administered according to actual body weight ABW may lead to adverse outcomes due to overdose For this reason some approaches recommend adjusting perioperative medications according to IBW instead of ABW The effects of WS and its components used in liposuction on patient outcomes have been examined in many studies but the IBWs of the patients have not been taken into consideration This study aimed to examine the effect of WSs calculated according to the IBW on postoperative complications and adverse events
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None