Ignite Creation Date:
2024-05-06 @ 8:07 PM
Last Modification Date:
2024-10-26 @ 3:20 PM
Study NCT ID:
NCT06251713
Status:
RECRUITING
Last Update Posted:
2024-02-28
First Post:
2024-01-15
Brief Title:
Fluid-removal Guided by VeXUS Score With Usual Care in Patients With Acute Kidney Injury After Cardiac Surgery
Sponsor:
Hospices Civils de Lyon
Organization:
Hospices Civils de Lyon
Study Overview
Official Title:
Feasibility of a Randomised Trial Comparing a Fluid-removal Guided by VeXUS Score With Usual Care in Patients With Acute Kidney Injury After Cardiac Surgery a Pilot Randomised Trial
Status:
RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
VeXUS
Brief Summary:
Acute kidney injury affects more than 30 of patients after cardiac surgery and is associated with an excess in mortality There is a clinical continuum between acute kidney injury transient if 48h persistent if 48h the development of acute kidney and chronic renal failure Each of these entities characterising renal recovery is associated with an increase in long-term morbidity and mortality Fluid management in patients with acute kidney injury is challenging as both hypovolaemia and hypervolaemia are detrimental Venous congestion reflecting intravascular hypervolaemia is a well-established haemodynamic factor contributing to acute kidney injury after cardiac surgery An ultrasound score based on the venous doppler pattern explored in intra-abdominal organs has recently been developed and is a better predictor of acute kidney injury than central venous pressure Whether using the VeXUS score to guide fluid removal in haemodynamically stabilised patients could promote renal recovery after acute kidney injury remains to be investigated
Before designing a large randomised trial to test such a strategy its feasibility in a pilot randomised trial is assessed
Before designing a large randomised trial to test such a strategy its feasibility in a pilot randomised trial is assessed
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None