Ignite Creation Date:
2024-05-06 @ 8:06 PM
Last Modification Date:
2024-10-26 @ 3:20 PM
Study NCT ID:
NCT06251362
Status:
RECRUITING
Last Update Posted:
2024-04-11
First Post:
2023-12-12
Brief Title:
Effects of Sleep Restriction on Female Soccer Players Physical Performance Muscle Damage Inflammation and BDNF Levels
Sponsor:
University School of Physical Education Krakow Poland
Organization:
University School of Physical Education Krakow Poland
Study Overview
Official Title:
The Impact of Sleep Restriction on Physical Performance Markers of Muscle Damage Inflammation and Brain-derived Neurotrophic Factor BDNF Levels in Female Soccer Players
Status:
RECRUITING
Status Verified Date:
2024-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This research aims to investigate the interplay between menstrual cycles sleep patterns and athletic performance Before experimental sessions participants will maintain menstrual diaries for three months and complete assessments for sleep disorders and chronotype Sleep duration will be objectively measured over five nights using actigraphy complemented by sleep-related data from an actigraph and the Karolinska Sleep Diary
The study involves two sessions normal sleep based on habitual duration and restricted sleep reduced by 3 hours Athletes will engage in a simulated match-play game before both sessions followed by comprehensive performance tests the next day Blood samples will be collected at three intervals to analyze hormonal profiles including progesterone and estradiol markers of muscle damage inflammation stress such as TNF-α IL-6 CRP myoglobin cortisol testosterone and brain-derived neurotrophic factor BDNF
On Day 1 pre- and post-training blood samples will be obtained and participants will wear an actigraph adhere to specified bedtime routines and report activities restricted sleep group Day 2 involves completing a sleep diary refraining from caffeine responding to questionnaires assessing readiness to train and mood and undergoing performance tests followed by self-reporting of pain levels and perceived exertion using established scales VAS RPE 6-20
The study involves two sessions normal sleep based on habitual duration and restricted sleep reduced by 3 hours Athletes will engage in a simulated match-play game before both sessions followed by comprehensive performance tests the next day Blood samples will be collected at three intervals to analyze hormonal profiles including progesterone and estradiol markers of muscle damage inflammation stress such as TNF-α IL-6 CRP myoglobin cortisol testosterone and brain-derived neurotrophic factor BDNF
On Day 1 pre- and post-training blood samples will be obtained and participants will wear an actigraph adhere to specified bedtime routines and report activities restricted sleep group Day 2 involves completing a sleep diary refraining from caffeine responding to questionnaires assessing readiness to train and mood and undergoing performance tests followed by self-reporting of pain levels and perceived exertion using established scales VAS RPE 6-20
Detailed Description:
Before commencing experimental sessions the menstrual cycles of the participants will be assessed using a menstrual diary spanning three months before the sessions Additionally each athlete will be asked to complete a questionnaire for screening sleep disorders PSQI and a chronotype classification questionnaire MEQ The average sleep duration over five consecutive nights will be measured using actigraphy this analysis will determine the length of sleep allocated during experimental sessions Sleep-related parameters will be recorded using an actigraph MotionWatch8 and confirmed using the Karolinska Sleep Diary KSD
The project involves two experimental sessions each spanning two days under two different conditions a normal sleep NS habitual sleep duration determined from the analysis of five consecutive nights and b restricted sleep RS sleep reduced by 3 hours during the nocturnal period compared to NS Participants will perform a simulation match-play game SAFT90 before NS and RS followed by performance tests on the following day Blood samples will be collected at three-time points a pre-training b post-training and c before morning tests on the second day of the experiment Biochemical analysis of the blood will include progesterone and estradiol for menstrual cycle analysis as well as parameters related to muscle damage inflammatory state and stress levels TNF-α IL-6 CRP myoglobin hematology cortisol testosterone Additionally the level of brain-derived neurotrophic factor BDNF will be analyzed
Day 1 of the experiment Immediately before training the first blood collection 8 ml will occur to analyze the necessary blood biochemical parameters Subsequently athletes will undergo a standardized afternoon training session including a simulation match-play game SAFT90 Another blood sample will be taken immediately after the exercise Participants will be asked to wear an actigraph on their non-dominant wrist and consume dinner according to the provided recommendations They will be instructed to go to bed according to a specified schedule NS or RS Additionally participants will be instructed to spend the time before bedtime engaged in routine evening activities excluding stimulants like coffee or additional exercise Participants with restricted sleep will also be requested to report their activities every 30 minutes until they go to bed using an internet communicator
Day 2 of the experiment Participants will complete the Karolinska Sleep Diary upon waking up They will also be asked to abstain from consuming caffeine-containing foods and to have breakfast following the provided recommendations Before the session begins participants will complete a readiness to train questionnaire RTQ and a mood assessment questionnaire POMS Blood samples will be collected followed by specific football-related performance tests a repeated high-intensity effort capacity Yo-Yo test b lower limb power vertical jump c maximal acceleration 3x30 m sprints d agility with and without the ball Zig-Zag Test Immediately after the performance tests participants will indicate their pain level Visual Analogue Scale VAS and rate their perceived exertion RPE 6-20
The project involves two experimental sessions each spanning two days under two different conditions a normal sleep NS habitual sleep duration determined from the analysis of five consecutive nights and b restricted sleep RS sleep reduced by 3 hours during the nocturnal period compared to NS Participants will perform a simulation match-play game SAFT90 before NS and RS followed by performance tests on the following day Blood samples will be collected at three-time points a pre-training b post-training and c before morning tests on the second day of the experiment Biochemical analysis of the blood will include progesterone and estradiol for menstrual cycle analysis as well as parameters related to muscle damage inflammatory state and stress levels TNF-α IL-6 CRP myoglobin hematology cortisol testosterone Additionally the level of brain-derived neurotrophic factor BDNF will be analyzed
Day 1 of the experiment Immediately before training the first blood collection 8 ml will occur to analyze the necessary blood biochemical parameters Subsequently athletes will undergo a standardized afternoon training session including a simulation match-play game SAFT90 Another blood sample will be taken immediately after the exercise Participants will be asked to wear an actigraph on their non-dominant wrist and consume dinner according to the provided recommendations They will be instructed to go to bed according to a specified schedule NS or RS Additionally participants will be instructed to spend the time before bedtime engaged in routine evening activities excluding stimulants like coffee or additional exercise Participants with restricted sleep will also be requested to report their activities every 30 minutes until they go to bed using an internet communicator
Day 2 of the experiment Participants will complete the Karolinska Sleep Diary upon waking up They will also be asked to abstain from consuming caffeine-containing foods and to have breakfast following the provided recommendations Before the session begins participants will complete a readiness to train questionnaire RTQ and a mood assessment questionnaire POMS Blood samples will be collected followed by specific football-related performance tests a repeated high-intensity effort capacity Yo-Yo test b lower limb power vertical jump c maximal acceleration 3x30 m sprints d agility with and without the ball Zig-Zag Test Immediately after the performance tests participants will indicate their pain level Visual Analogue Scale VAS and rate their perceived exertion RPE 6-20
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None