Ignite Creation Date:
2024-05-06 @ 8:06 PM
Last Modification Date:
2024-10-26 @ 3:20 PM
Study NCT ID:
NCT06257381
Status:
COMPLETED
Last Update Posted:
2024-07-09
First Post:
2024-02-05
Brief Title:
Maximal Oxygen Uptake VO2max in Patients With COPD
Sponsor:
Rigshospitalet Denmark
Organization:
Rigshospitalet Denmark
Study Overview
Official Title:
Maximal Oxygen Uptake VO2max in Patients With COPD a Test-Retest Reliability Study
Status:
COMPLETED
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
COPD-MAX
Brief Summary:
Patients with chronic obstructive pulmonary disease COPD facing a decline in lung function and compromised quality of life often benefit from regular exercise 1 Assessing their cardiorespiratory fitness through maximal oxygen uptake VO2max is crucial 2 yet research on its validity and reliability in COPD patients remains sparse This study aims to fill this gap examining the content validity and test-retest reliability of the VO2-max test in COPD comparing it with healthy controls
Detailed Description:
Introduction and background Patients with COPD face a challenging journey characterized by a progressive loss of lung function ultimately resulting in a diminished quality of life exercise limitations and heightened vulnerability to disability and premature mortality Recognizing the pivotal role of regular exercise in enhancing the well-being of COPD patients it becomes crucial to evaluate their cardiorespiratory fitness through parameters such as maximal oxygen uptake VO2max This metric serves as a cornerstone in assessing the maximal capacity of the cardiovascular system to deliver oxygen to working muscles and the muscles ability to utilize oxygen during sustained exercise
In broader health contexts high VO2max has been established as a key indicator inversely correlated with the risk of cardiovascular diseases and mortality However despite the acknowledged importance of VO2max there is a notable gap in research focusing specifically on VO2max of COPD patients The need for a thorough examination of the content validity of the VO2-max test in the context of COPD along with an assessment of its test-retest reliability day-to-day variation has not been adequately addressed especially in comparison with healthy individuals While regular exercise has proven to be a transformative factor in improving the quality of life for COPD patients there remains a critical need to explore the reliability of VO2-max testing within this population Not only does COPD induce a decline in physical activity but it can also contribute to a reduction in VO2-max Consequently understanding the validity and test-retest reliability of VO2-max testing in COPD becomes paramount
Aim To compare the validity and test-retest reliability of the VO2-max test in COPD patients compared with healthy controls
Perspective The results are relevant for designing future studies of VO2max and VO2kinetics as outcomes in COPD patients
In broader health contexts high VO2max has been established as a key indicator inversely correlated with the risk of cardiovascular diseases and mortality However despite the acknowledged importance of VO2max there is a notable gap in research focusing specifically on VO2max of COPD patients The need for a thorough examination of the content validity of the VO2-max test in the context of COPD along with an assessment of its test-retest reliability day-to-day variation has not been adequately addressed especially in comparison with healthy individuals While regular exercise has proven to be a transformative factor in improving the quality of life for COPD patients there remains a critical need to explore the reliability of VO2-max testing within this population Not only does COPD induce a decline in physical activity but it can also contribute to a reduction in VO2-max Consequently understanding the validity and test-retest reliability of VO2-max testing in COPD becomes paramount
Aim To compare the validity and test-retest reliability of the VO2-max test in COPD patients compared with healthy controls
Perspective The results are relevant for designing future studies of VO2max and VO2kinetics as outcomes in COPD patients
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None