Ignite Creation Date:
2024-05-06 @ 8:06 PM
Last Modification Date:
2024-10-26 @ 3:20 PM
Study NCT ID:
NCT06253819
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-02-12
First Post:
2024-01-07
Brief Title:
Investigation of Respiratory Functions Exercise Endurance and Functional Capacity in Geriatric Individuals With Metabolic Syndrome
Sponsor:
Kırıkkale University
Organization:
Kırıkkale University
Study Overview
Official Title:
Investigation of Respiratory Functions Exercise Endurance and Functional Capacity in Geriatric Individuals With Metabolic Syndrome
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Metabolic syndrome MetS or syndrome X which is increasingly prevalent in the world and in our country is a disease that includes abdominal obesity dyslipidaemia impaired glycaemic control and hypertension components It causes cardiovascular events such as myocardial hypertrophy left ventricular diastolic dysfunction atrial dilatation and atrial fibrillation Low physical activity level may be caused by various factors such as environmental and genetic factors age race sarcopenia poor eating habits postmenopausal period and smoking history It has been reported that factors such as genetic differences diet physical activity age gender and eating habits affect the prevalence of MetS and its components Metabolic syndrome is a fatal endocrinopathy that starts with insulin resistance and is accompanied by systemic disorders such as abdominal obesity glucose intolerance or diabetes mellitus dyslipidaemia hypertension and coronary artery disease CAD Although the prevalence of metabolic syndrome which is accepted as an important public health problem in both developed and developing countries varies according to different geographical and ethnic characteristics definitions used age and gender characteristics of populations it shows a global increase and is considered as a pandemic affecting 20 to 30 of the adult population in many countries The likelihood of metabolic syndrome increases in geriatric individuals due to some changes caused by aging In a study conducted in geriatric individuals in our country the incidence of metabolic syndrome was reported as 360
As a result of ageing degenerative changes in the central and peripheral vestibular system have been found With age the ability to regulate movement is impaired as a result of insufficient information in any of the sensory receptors or any disorder affecting the processing of these messages This directly affects functional capacity In elderly individuals tolerance to physical effort decreases due to a decrease in maximal oxygen consumption and maximal heart rate Systolic and diastolic blood pressure increases The number of respirations per minute increases in the elderly due to the difficulty in chest cage adaptationAging causes a decrease in the elasticity of the lung The respiratory surface area which is up to 75 square metres m² in young adults due to damage to the inter-alveolar septum during aging decreases by approximately 3 m² per decade Systematic changes seen with aging also have negative effects on functional status and exercise endurance
In sarcopenia which is defined as a decrease in muscle mass and strength with advancing age there is an irreversible decrease in the number of muscle fibres and myofibrils contained in each muscle fibre From the age of 20 years to 70 years approximately 40 loss in muscle mass and 30-50 decrease in muscle strength occur It is stated that this loss starts at the age of 25 but muscle mass and muscle strength are lost at a rate of 1 per year from the age of 50
In geriatric rehabilitation patients functionality balance and fall problems have an important place On the other hand cardiac risk is increased in geriatric individuals and respiratory assessments have an important place Metabolic syndrome is 7 times more common in individuals with maximal oxygen consumption VO2 max below 29 mL-kg-1 -min-1 than in those with VO2 max above 355 mL-kg-1 -min-1 Metabolic syndrome directly affects the pulmonary system
In the light of the results obtained from the studies in the literature degenerative changes are observed in many systems in geriatric individuals and while the incidence of metabolic syndrome in these individuals is high the number of studies evaluating their effects is not sufficient Based on these deficiencies it is aimed to reveal the effects of respiratory muscle strength pulmonary function exercise endurance and functional level in geriatric individuals with metabolic syndrome
As a result of ageing degenerative changes in the central and peripheral vestibular system have been found With age the ability to regulate movement is impaired as a result of insufficient information in any of the sensory receptors or any disorder affecting the processing of these messages This directly affects functional capacity In elderly individuals tolerance to physical effort decreases due to a decrease in maximal oxygen consumption and maximal heart rate Systolic and diastolic blood pressure increases The number of respirations per minute increases in the elderly due to the difficulty in chest cage adaptationAging causes a decrease in the elasticity of the lung The respiratory surface area which is up to 75 square metres m² in young adults due to damage to the inter-alveolar septum during aging decreases by approximately 3 m² per decade Systematic changes seen with aging also have negative effects on functional status and exercise endurance
In sarcopenia which is defined as a decrease in muscle mass and strength with advancing age there is an irreversible decrease in the number of muscle fibres and myofibrils contained in each muscle fibre From the age of 20 years to 70 years approximately 40 loss in muscle mass and 30-50 decrease in muscle strength occur It is stated that this loss starts at the age of 25 but muscle mass and muscle strength are lost at a rate of 1 per year from the age of 50
In geriatric rehabilitation patients functionality balance and fall problems have an important place On the other hand cardiac risk is increased in geriatric individuals and respiratory assessments have an important place Metabolic syndrome is 7 times more common in individuals with maximal oxygen consumption VO2 max below 29 mL-kg-1 -min-1 than in those with VO2 max above 355 mL-kg-1 -min-1 Metabolic syndrome directly affects the pulmonary system
In the light of the results obtained from the studies in the literature degenerative changes are observed in many systems in geriatric individuals and while the incidence of metabolic syndrome in these individuals is high the number of studies evaluating their effects is not sufficient Based on these deficiencies it is aimed to reveal the effects of respiratory muscle strength pulmonary function exercise endurance and functional level in geriatric individuals with metabolic syndrome
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None