Ignite Creation Date:
2024-05-06 @ 8:05 PM
Last Modification Date:
2024-10-26 @ 3:20 PM
Study NCT ID:
NCT06257446
Status:
RECRUITING
Last Update Posted:
2024-02-14
First Post:
2024-01-31
Brief Title:
InformationSeekingMesolimbicEngagementStudy1
Sponsor:
Temple University
Organization:
Temple University
Study Overview
Official Title:
The Influence of Mesolimbic-hippocampal Interactions on Episodic Memory During Active Information Seeking
Status:
RECRUITING
Status Verified Date:
2024-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Study 1 will use a novel Game Show task in which the investigators manipulate participants agency to control their learning environment to specify unguided exploration
Detailed Description:
Study 1 will use a novel Game Show task in which the investigators manipulate participants agency to control their learning environment to specify unguided exploration In the encoding session participants play the producer for a game show On each trial participants are shown a trial-unique contestant 2s and then they select one of 3 presented doors to reveal a hidden object 4 seconds The selected door is then highlighted 2-4s which is then removed to show a trial-unique object image which is framed as a prize 2s On exploration trials participants actively select which door to open On control trials the participant is forced to select a highlighted door fostering passive rather than active information seeking Unbeknownst to participants there is no relationship between selected doors and revealed objects as objects are pre-selected for each trial Thus timing motor demands and visual information are fixed across conditions Participants will complete 3 runs of both the exploration and control condition with each run containing 20 trials Temporal jitters are placed between cues and outcomes and between trials as determined by design optimization software77 Run will be pseudo-randomized across participants so no more than 2 runs of the same condition will appear in a row Following encoding participants will complete immediate and delayed item-associative memory test On each trial of the memory test participants will view the characters presented during exploration and control trials as well as new foil characters If a participant indicates that they have previously seen a character before the participants will be shown three object images encountered during encoding and decide which item served as a prize for that specific character In this way the investigators can resolve memory for contestants ie cues and associative binding across contestants and prizes ie cue-outcome Participants memory will be tested for half the stimuli immediately and at a 24-hour delay
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| R01DA055259 | NIH | None | httpsreporternihgovquickSearchR01DA055259 |