Ignite Creation Date:
2024-05-06 @ 8:05 PM
Last Modification Date:
2024-10-26 @ 3:20 PM
Study NCT ID:
NCT06255067
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-02-12
First Post:
2023-12-26
Brief Title:
Efficacy of Noisome as A Carrier of Locally Delivered Minocycline Hydrochloride Gel
Sponsor:
Ain Shams University
Organization:
Ain Shams University
Study Overview
Official Title:
Efficacy of Noisome as A Carrier of Locally Delivered Minocycline Hydrochloride Gel in Stage II or Stage III Periodontitis A Randomized Controlled Clinical Trial With Biochemical Analysis
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The goal of this clinical trial is to compare the efficacy of Noisome as carrier of minocycline hydrochloride gel to minocycline hydrochloride in Stage II or Stage III Periodontitis The main questions it aims to answer are
Is the Noisome carrier of minocycline hydrochloride has an effect in comparing to minocycline hydrochloride in Stage II or Stage III Periodontitis
what is the release profile of of minocycline hydrochloride noisome gel and minocycline hydrochloride gel Participants will be asked to maintain oral hygiene after application of treatment Researchers will compare the effect of noisome as a carrier of locally delivered minocycline hydrochloride gel to minocycline hydrochloride gel in stage II or stage III periodontitis patients as an adjunct to non-surgical periodontal treatment to see if Plaque Index PI Gingival indexClinical attachment level CAL Periodontal Pocket Depth decreased or not
Is the Noisome carrier of minocycline hydrochloride has an effect in comparing to minocycline hydrochloride in Stage II or Stage III Periodontitis
what is the release profile of of minocycline hydrochloride noisome gel and minocycline hydrochloride gel Participants will be asked to maintain oral hygiene after application of treatment Researchers will compare the effect of noisome as a carrier of locally delivered minocycline hydrochloride gel to minocycline hydrochloride gel in stage II or stage III periodontitis patients as an adjunct to non-surgical periodontal treatment to see if Plaque Index PI Gingival indexClinical attachment level CAL Periodontal Pocket Depth decreased or not
Detailed Description:
This study is designed to be a Randomized Controlled blinded clinical trial the eligible participants will be randomly allocated for one of the two comparative parallel-Groups test and control group The interventions will be prepared by the pharmacist and coded and the whole-time frame for the study will be 18 weeks
The intervention to all participants will be Non-surgical debridement the the test group will receive the Noisome minocycline hydrochloride control group will receive minocycline hydrochloride
The intervention to all participants will be Non-surgical debridement the the test group will receive the Noisome minocycline hydrochloride control group will receive minocycline hydrochloride
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
False
Is an FDA AA801 Violation?:
None