Ignite Creation Date:
2024-05-06 @ 8:05 PM
Last Modification Date:
2024-10-26 @ 3:20 PM
Study NCT ID:
NCT06241924
Status:
RECRUITING
Last Update Posted:
2024-02-12
First Post:
2024-01-26
Brief Title:
Oscillatory Activity in Basal Ganglia Circuits During Normal and Pathological Movement
Sponsor:
University Hospital Bordeaux
Organization:
University Hospital Bordeaux
Study Overview
Official Title:
Oscillatory Activity in Basal Ganglia Circuits During Normal and Pathological Movement
Status:
RECRUITING
Status Verified Date:
2024-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
BAG-OSMOV
Brief Summary:
The expression of hypokinetic and hyperkinetic motor symptoms is accompanied by pathological synchronous oscillations of neuronal activity in this cortico-subcortical network with a wide frequency range
The purpose of this research is to study cortico-subcortical oscillations and their synchronization in two pathologies emblematic of hypokinetic Parkinsons disease and hyperkinetic epilepsies phenomena using a simple motor task and comparing different situations
The purpose of this research is to study cortico-subcortical oscillations and their synchronization in two pathologies emblematic of hypokinetic Parkinsons disease and hyperkinetic epilepsies phenomena using a simple motor task and comparing different situations
Detailed Description:
In order to define the link between the characteristics of the oscillations frequency amplitude phase relation within this cortico-subcortical network and movement normal or pathological in humans a simple motor task of grippingpulling a lever has been designed
The local field potentials LFPs will be collected during the same motor task in
i patients with Parkinsons disease using a high-resolution electroencephalogram EEG and the PERCEPTTM system Medtronic equipped with a sensing function for deep LFP recordings and in EEG-HR for high resolution for cortical recordings
ii patients with focal drug-resistant epilepsy during a pre-surgical assessment by stereo-electro-encephalography SEEG The SEEG allows the recording of both the cortex and the subcortical regions in a concomitant manner and a direct correlation can be studied
The local field potentials LFPs will be collected during the same motor task in
i patients with Parkinsons disease using a high-resolution electroencephalogram EEG and the PERCEPTTM system Medtronic equipped with a sensing function for deep LFP recordings and in EEG-HR for high resolution for cortical recordings
ii patients with focal drug-resistant epilepsy during a pre-surgical assessment by stereo-electro-encephalography SEEG The SEEG allows the recording of both the cortex and the subcortical regions in a concomitant manner and a direct correlation can be studied
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None