Ignite Creation Date:
2024-05-06 @ 8:05 PM
Last Modification Date:
2024-10-26 @ 3:20 PM
Study NCT ID:
NCT06243692
Status:
RECRUITING
Last Update Posted:
2024-03-29
First Post:
2024-01-29
Brief Title:
Lacosamide Versus Topiramate in Migraine
Sponsor:
Kafrelsheikh University
Organization:
Kafrelsheikh University
Study Overview
Official Title:
Lacosamide Versus Topiramate in Migraine a Ranodmized Trial
Status:
RECRUITING
Status Verified Date:
2024-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Investigators aim to compare the effect of lacosamide versus topiramate in migraine by assessing the absolute reduction in MMD in each group the percentage of patients who achieved 50 reduction in the monthly headache days frequency compared to the baseline frequency
Detailed Description:
Investigators will enroll 600 migraine patients who are diagnosed according to ICHD3-beta criteria in our study and will use a questionnaire to detect their demographic and clinical features disease duration attack frequency and duration pain intensity assessed by the visual analogic scale and we have two groups the first group will include 300 patients and will receive 50 mg lacosamide twice daily and Acetaminophen 500-1000 mg in acute attack and the second group will receive topiramate100 mg per day and Acetaminophen 500-1000 mg in acute attack for at least three months Investigators will assess The number of migraine days after three months of treatment and the percentage of patients who achieved 50 reduction in the monthly headache days frequency compared to the baseline frequency 14 HIT-6 score reduction in each group after three months of treatment The safety of lacosamide was evaluated by monitoring and documenting treatment-emergent adverse events TEAE in patients through regular follow-up procedures for three months
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
True
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
True
Is an FDA AA801 Violation?:
None