Ignite Creation Date:
2024-05-06 @ 8:04 PM
Last Modification Date:
2024-10-26 @ 3:20 PM
Study NCT ID:
NCT06242704
Status:
RECRUITING
Last Update Posted:
2024-07-10
First Post:
2024-01-16
Brief Title:
Train Your Brain 20 - Improving Memory and Decision Making Among Youth
Sponsor:
Henry Ford Health System
Organization:
Henry Ford Health System
Study Overview
Official Title:
Train Your Brain 20 Improving Memory and Decision Making to Improve Outcomes Among Youth - A Randomized Controlled Trial
Status:
RECRUITING
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The goal of this clinical trial is to deliver a computer-based working memory training program to improve delay discounting DD and prevent substance misuse among at-risk adolescents in a traditionally underserved area Results from the study will inform future substance use prevention efforts targeted at youth exposed to adverse childhood experiences Findings will also refine future models of intervention delivery in traditionally underserved communities
The main aims of the project are are
1 To examine to examine changes in hypothesized mechanisms of substance use initiation and escalation and 2 to assess whether changes in DD are a mechanism for reducing substance misuse during early adolescence The investigators will evaluate whether changes in DD following active treatment predict substance use outcomes over the three-month follow-up period
The main aims of the project are are
1 To examine to examine changes in hypothesized mechanisms of substance use initiation and escalation and 2 to assess whether changes in DD are a mechanism for reducing substance misuse during early adolescence The investigators will evaluate whether changes in DD following active treatment predict substance use outcomes over the three-month follow-up period
Detailed Description:
Youth exposed to early childhood adversity are at increased risk for engaging in problematic substance use leading to myriad negative health outcomes including HIV exposure injury and impaired driving Adolescents from low-resource communities evidence elevated rates of exposure to adverse childhood experiences yet have limited access to evidence-based preventative interventions Thus there is a critical need for services that can feasibly target specific mechanisms linking early adversity to the onset and escalation of substance use in traditionally underserved communities
One such target is delay discounting DD the tendency to select small immediately available rewards relative to larger delayed rewards DD has been linked to early substance use initiation and more frequent and severe use across adolescence Moreover youth exposed to early childhood adversity evidence more problematic levels of DD indicating that DD may be a pathway by which early trauma exposure leads to drug and alcohol use
Research from the investigative team suggests that computer-based interventions targeting proximal cognitive skills specifically working memory can improve rates of DD Moreover computerized interventions are highly transportable and scalable making them ideal for dissemination in low-resource communities The current project proposes to pilot a computer-based working memory WM training program to improve DD and prevent substance use among at-risk adolescents in a traditionally underserved area
One such target is delay discounting DD the tendency to select small immediately available rewards relative to larger delayed rewards DD has been linked to early substance use initiation and more frequent and severe use across adolescence Moreover youth exposed to early childhood adversity evidence more problematic levels of DD indicating that DD may be a pathway by which early trauma exposure leads to drug and alcohol use
Research from the investigative team suggests that computer-based interventions targeting proximal cognitive skills specifically working memory can improve rates of DD Moreover computerized interventions are highly transportable and scalable making them ideal for dissemination in low-resource communities The current project proposes to pilot a computer-based working memory WM training program to improve DD and prevent substance use among at-risk adolescents in a traditionally underserved area
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None